Flores I, Huang L

Language: Spanish
References: 10
Page: 617-620
PDF size: 161.48 Kb.

ABSTRACT

In 1990, Takotsubo cardiomyopathy (TCM) was first discovered and reported by a Japanese cardiovascular specialist. This entity has emerged as a unique cardiomyopathy with world - wide recognition, mimicking acute coronary syndrome. It occurs more often in postmenopausal elderly women, is characterized by a transient hypokinesis of the left ventricular (LV) apex, and is associated with emotional or physical stress. Wall motion abnormality of the LV apex is generally transient and resolves within a few days to several weeks. Although TCM has been considered a benign condition, it now carries a small but important risk for adverse outcomes. The exact pathogenesis of TCM is unknown, but various hypotheses have been suggested and discussed, currently, catecholamineinduced cardiotoxicity and microvasculature dysfunction are the most supported theories. This article aimed to review this newly recognized cardiomyopathy, paying particular attention to clinical characteristics, pathophysiology, diagnosis, and treatment.

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