2016, Number 2
TIMI score as a predictor of death in patients with acute myocardial infarction without percutaneous coronary intervention
Language: Spanish
References: 19
Page: 111-116
PDF size: 253.34 Kb.
ABSTRACT
Introduction: Acute myocardial infarction (AMI) is a frequent disorder, associated with high morbidity and mortality; therefore the implementation of risk predictive models is required.Objective: To determine the value of TIMI score to predict early death risk in patients with ST-elevation AMI.
Method: Patients with a diagnosis of ST-elevation AMI admitted in the intensive care unit (ICU) at "Dr. Miguel Enríquez" University Hospital were consecutively included. Death risk in ICU was assessed by using a logistic regression model, according to TIMI score at admission.
Results: 115 patients were analyzed. Mean TIMI score was 5.04 (standard deviation 2.7) and the mortality rate was 10.4%. Logistic regression analysis showed that the higher TIMI score was associated with increased death risk in ICU (OR 1.47 [95% CI 1.17-1.83]; p= 0.001); with adequate model calibration (Hosmer-Lemeshow test; χ2 =5.82; p=0.324), and an area under the receiver-operating characteristic curve of 0.76 [(95% CI 0.60-0.93); p= 0.003].
Conclusions: TIMI score is a good tool to predict the risk of early death in patients with ST-elevation AMI assisted in centers without percutaneous coronary intervention.
REFERENCES
O'Gara PT, Kushner FG, Ascheim DD, Casey DE, Chung MK, de Lemos JA, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2013;127:e362-425.
Abu-Assi E, García-Acuña JM, Ferreira-González I, Peña-Gil C, Gayoso-Diz P, González-Juanatey JR. Evaluating the performance of the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the ACC/AHA Guidelines (CRUSADE) bleeding score in a contemporary Spanish cohort of patients with non-ST-segment elevation acute myocardial infarction. Circulation. 2010;121:2419- 26.
Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, et al. TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for treatment of infarcting myocardium early II trial substudy. Circulation. 2000;102:2031-7.
Aragam KG, Tamhane UU, Kline-Rogers E, Li J, Fox KA, Goodman SG, et al. Does simplicity compromise accuracy in ACS risk prediction? A retrospective analysis of the TIMI and GRACE risk scores. PLoS ONE [Internet]. 2009 [citado 11 Feb 2016];4:e7947. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2 776353/pdf/pone.0007947.pdf
Cordero Sandoval QM, Ramírez Gómez JI, Moreno-Martínez FL, González Alfonso O. Valor predictivo de algunos modelos de estratificación de riesgo en pacientes con infarto agudo de miocardio con elevación del ST. CorSalud [Internet]. 2013 [citado 11 Feb 2016];5:57-71. Disponible en: http://www.corsalud.sld.cu/sumario/2013/v5n1a1 3/estratificacion.html