2015, Number 6
Clinical and epidemiological characterization of preterm infants with early-onset infection
Language: Spanish
References: 22
Page: 1014-1027
PDF size: 645.35 Kb.
ABSTRACT
Introduction: early neonatal infections are defined as the ones occurring within the first 72 hours of life.Objective: to characterize preterm infants with early-onset infection clinically and epidemiologically.
Materials and methods: an observational, descriptive and cross-sectional study was conducted in the Neonatal Intensive Care Unit, at Abel Santamaría Cuadrado General Teaching Hospital in Pinar del Rio, during January 2013 to November 2014. The universe included 662 preterm infants. The sample consisted of 66 infants diagnosed with early-onset infection considering the inclusion criteria. Variables such as weight, gender, gestational age, maternal and perinatal factors, presentation, germs and survival rate were considered. Percentage, mean and standard deviation method was used.
Results: infants weighting less than 1500 grams predominated (62.1%), female sex (56.1%) and the appropriate standards for gestational age (59.1%). Regarding maternal and perinatal variables, the vaginal infection prevailed 43.9%, premature rupture of membranes showed more than 18 hours (21.2%) and spontaneous labor (71.2%). Prophylaxis for group-B of streptococcus was performed in 65.2% mothers; 68.2% of the infants were born by cesarean sections. Bloodstream infection was the most frequent way of presentation (54.5%) and E. coli germ predominated (18.2%). Survival rate was 95.5%.
Conclusions: early-onset sepsis is a frequent morbidity factor in preterm infants; it constitutes a major health problem; however the survival rates were high.
REFERENCES
Pérez DM, Mulet BB, Rodríguez NO, Legrá GM. Factores maternos relacionados con el bajo peso al nacer. Rev Cubana Obstet Ginecol [serial on the Internet]. 2011 Dec [cited 2012 May 14]; 37(4): 489-501. Available from: http:// scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138-600X2011000400006 &lng=en
Vélez GM, Barros FC, Echavarría RG, Hormaza AP. Prevalencia de bajo peso al nacer y factores maternos asociados: Unidad de atención y Protección Materno Infantil de la Clínica Universitaria Bolivariana, Medellín, Colombia. Rev Colomb Obstet Ginecol [periódico na Internet]. 2006 Dez [citado 2012 Maio 10]; 57(4): 264-270. Disponible en: http://www.scielo.org.co/scielo.php?script= sci_arttext&pid=S0034-74342006000400005&lng=pt
Stoll BJ, Hansen NI, Sánchez PJ, Faix RG, Poindexter BB, Krisa P, et al. Sepsis neonatal de inicio temprano. Pediatrics. [Internet]. 2011 [citado 20 Abr de 2015]; [aprox . 10 p.]. Disponible en: http://www.pediatrics.org/cgi/content/full/127/5/817"JulHYPERLINK "http://www.pediatrics.org/cgi/content/full/127/5/817"2015];127
Fernández Díaz N, de Estrada Riverón JD, Díaz Cuéllar F. Morbilidad y mortalidad por sepsis neonatal precoz. Rev Cubana Pediatr [Internet]. 2010 [citado 12 Abr 2014]; 82(2): [aprox. 22 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034- 75312010000200003"pid=S0034-75312010000200003
Álvarez Rodríguez JM, Soler Chacón M, Guerra Arévalo E, García Guerrero Y, Sánchez Díaz L. Epidemiología de las infecciones de inicio precoz en el Servicio de Neonatología del Hospital General "Orlando Pantoja Tamayo". MEDISAN [Internet]. 2013 [citado 28 Abr 2015]; 17(12): [aprox. 2 p.]. Disponible en: http://bvs.sld.cu/revistas/san/vol17_12_13/san041712.htm
García Muñoz RF, Galán HG, Figueras AJ, García Alix Pérez A. Outcomes of Very-Low-Birth-Weight Infants Exposed to Maternal Clinical Chorioamnionitis: A Multicentre Study. Neonatology [Internet]. 2014 [citado 28 Abr 2015]; 106(3): [aprox. 6 p.]. Disponible en: http://www.karger.com/Article/AbstrHYPERLINK "http://www.karger.com/Article/Abstract/363127"act/363127