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2015, Number 4

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Rev Cubana Med Gen Integr 2015; 31 (4)

Pulmonary tuberculosis/HIV infections: Association between immune status and radiological findings

de la Paz BT, Verdasquera CD, Millán MJC, Portela RD, Jiménez PNA, Kitchin WMA

Language: Spanish
References: 18
Page: 375-382
PDF size: 109.64 Kb.


ABSTRACT

Introduction: HIV infection affects cellular immunity, thus increasing host susceptibility to infection by Mycobacterium tuberculosis. In primary health care the role played by the family physician and the family nurse is essential to prevent these complications in infected patients.
Objective: Determine the association between immune status and radiological findings in HIV/AIDS patients with pulmonary TB.
Methods: Descriptive study of clinical cases. A hundred twenty patients with HIV/AIDS and positive sputum culture for Mycobacterium tuberculosis were the universe of our study. These patients were treated at the Hospital of Pedro Kouri Institute of Tropical Medicine from January 2004 to December 2010.
Results: Patients with T CD4+ counts below 200 cel/µL had 5.70 times higher chance of presenting a primary radiological pattern (OR: 5.70; CI 2, 48- 13,09; p = 0.00 ). No statistically significant association between the radiological post primary pattern and T CD4+ count was found. Patients with T CD4+ counts above 200 cel/µL had 1.96 times higher chance of presenting normal chest Rx, but it was not statistically significant.
Conclusions: The radiographic pattern of primary TB is associated with T CD4+ count below 200 cells /µL and the absence of radiographic abnormalities in patients with counts of TCD4 + above 200 cells/µL, did not rule out pulmonary TB/HIV co-infection.


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