2016, Number 1
Linfoma de linfocitos pequeños/leucemia linfocítica crónica
Language: Spanish
References: 12
Page: 78-86
PDF size: 260.14 Kb.
ABSTRACT
A female patient of 70 years old, personal medical history of bronchial asthma, high blood pressure and diabetes mellitus type 2 with chronic renal failure, stage V secondary to this, multiple entries in hospital by developing respiratory sepsis and need for peritoneal dialysis. It was found giant splenomegaly in imaging study during one of the entries. She evolved unfavorably with hypotension, fever, diffuse abdominal pain. The pathological findings showed a lymphoma of small lymphocytes/chronic lymphocytic leukemia cells. Stage IV. With infiltration to multiple viscera, including: lymph nodes, liver, spleen, lung, kidney and serous .The presence of pseudofoliculos is considered a morphological feature almost absolutely pathognomonic of the disease.REFERENCES
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Byrd JC, Gribben JG, Peterson BL, Grever MR, Lozanski G, Lucas DM, et al. Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy. J Clin Oncol [Internet]. 2006 [citado 21 Ene 2013];24(3):437-43. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/16344317
Basquiera A, Márquez M, Vijnovich A, Picon A, Zerga M. Linfoma difuso de células grandes B [Internet]. 2012 [citado 28 Mar 2013]. Disponible en: http://webcache.googleusercontent.com/search?q=cache:RXH5oOAdDGQJ:sah.org.ar/docs/251274.5B.SAH_GUIA2012_LinfomaCelulasGrandes_1.pdf+&cd=2&hl=es&ct=clnk&gl=cu