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ISSN 1561-2988 (Print)

2015, Number 1

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Rev Cubana Farm 2015; 49 (1)

Analysis of the antimicrobial susceptibility profile of bacteria isolated from bacteriemias in a university hospital

Filipini RR, Hörner R, Martini R, Silveira NM, Razia GL, Oliveira SS, Bottega A

Language: Portugués
References: 25
Page: 61-69
PDF size: 116.37 Kb.


ABSTRACT

Introduction: bacteremia is one of the most common and serious complications that mainly affect immunocompromised patients. It accounts for the extension of hospitalization and is related to high morbidity and mortality rates in inpatients.
Objective: to identify microorganisms associated with bacteremia and to analyze their antimicrobial susceptibility profile in a tertiary hospital.
Methods: retrospective and cross-sectional study including all the hemocultures that showed viable microorganism growth.
Results: one thousand eighty samples were evaluated in this study. The most isolated pathogen was Staphylococcus epidermidis (24%/n=259), followed by Staphylococcus hominis (6.8%/n=74). All Gram-positive bacteria were susceptible to Daptomycin, Tigecyline, Vancomycin and Linezolid. On the other hand, 42.31% of the isolated Coagulase-negative Staphylococcus were phenotipically characterized as methicillin-resistant (MRSCon).
Conclusions: the majority of bacteriemias was caused by Coagulase negative Staphylococcus with significant methicillin-resistance; consequently, the institution must reanalyze the antibiotic treatment mainly for hospitalized patients in critical care units.


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