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2015, Number 2

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Invest Medicoquir 2015; 7 (2)

Rash after amoxicillin treatment in adolescent with infectious mononucleosis

Alvaré ALE, Melo VMR, Lobato PMD, González CI, Verdecia GN
Full text How to cite this article

Language: Spanish
References: 9
Page: 324-330
PDF size: 798.80 Kb.


Key words:

amoxicillin, sensitization, to antibiotics, infectious mononucleosis, drug test.

ABSTRACT

It hasn't been clearly understood yet whether sensitization to antibiotics, the virus itself or transient loss of drug tolerance due to the virus ,is responsible for the development of maculopapular exanthemas following amoxicillin intake in patients with infectious mononucleosis. We aimed to examine whether sensitization to penicillin develop among patients with skin rash following amoxicillin treatment within infectious mononucleosis. One patient was investigated for drug sensitization by Prick, intradermal and patch test employing the penicillin’s main antigens. Prick test was positive and the intradermal test too. We think in relation of our data that our results confirmed that sensitization to amoxicillin may develop with in infectious mononucleosis.


REFERENCES

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  2. Laing GL, Kanwar BS. Drugs rashes in glandular fever. Lancet. 1967;290(7531):1418.

  3. Lara HP. Mononucleosis infecciosa. Revisión Bibliográfica. Rev Med Cos Cen. 2009;66(587):73-7.

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Invest Medicoquir. 2015;7