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2015, Number 2

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Rev Cubana Invest Bioméd 2015; 34 (2)

Arterial soft tissue and the correlation between biomechanical parameters and clinical aspects

Camue CE, González CRA, Cisneros HYA, Oropeza RYE, Pérez REO

Language: Spanish
References: 18
Page: 122-135
PDF size: 362.90 Kb.


ABSTRACT

Introduction: cerebrovascular diseases are common conditions. They are the main cause of death both in Cuba and worldwide, since they lead to the development of ischemic heart diseases. Biomechanical alterations of the arterial wall are early manifestations of atherosclerotic heart disease.
Objective: substantiate the relationship between biomechanical parameters of arterial soft tissue and risk factors for atherosclerosis.
Methods: biomechanical modeling was used to study the behavior of the vascular wall under the action of multiple risk factors.
Results: tangential and circumferential tensions on arterial tissue are related to areas of atheroma plaque formation and rupture. The presence of stenosis along the route of a fluid leads to important changes in both arterial pressure and tangential tensions, and encourages little resistance to circumferential tensions.
Conclusions: mechanical behavior of the arterial wall and its relationship to risk factors reveal the complexity of the processes occurring therein in both physiological and pathological conditions. Its characterization constitutes a tool for the integration of medical and engineering studies, mainly about areas of great artery curvature or bifurcation.


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