2015, Number S1
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Rev Med Inst Mex Seguro Soc 2015; 53 (S1)
Maternal and fetal outcome in Mexican women with rheumatoid arthritis
Saavedra MA, Sánchez A, Bustamante R, Miranda-Hernández D, Soliz-Antezana J, Cruz- Domínguez P, Morales S, Jara LJ
Language: Spanish
References: 26
Page: 24-29
PDF size: 78.58 Kb.
ABSTRACT
Objective: To report our experience in maternal-fetal outcome in women
with RA in a national medical referral center.
Methods: A retrospective analysis of the records of pregnant women
with rheumatoid arthritis attending at a Pregnancy and Autoimmune
Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes
such as disease activity, preclampsia/eclampsia, rate of live births, abortions,
stillbirths, preterm birth, weeks of gestation, birth weight, congenital
malformations and use of anti-rheumatic drugs were studied.
Results: We included 73 pregnancies in 72 patients. Disease activity
was documented in 47.2% of patients during pregnancy and/or postpartum
and 87.7 % of patients received some antirheumatic drug. Preclampsia
developed in 8.2 % of cases. The live birth rate was 98.6 %, with
preterm delivery in 15.9 % and low weight at term in 17.6% of cases.
Cesarean section was performed in 77.1 % of cases. The disease activity
was not associated with a higher percentage of maternal-fetal complications.
Conclusions: Our study showed that most patients do not experience
signifi cant activity of RA during pregnancy, fetal outcome is satisfactory
and disease activity did not appear to infl uence signifi cantly the obstetric
outcome.
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