2015, Number 6
Necrotizing fasciitis
Language: Spanish
References: 31
Page: 654-664
PDF size: 432.82 Kb.
ABSTRACT
Background: necrotizing fasciitis is the most challenging surgical infection that surgeons face. The complex management is due to the combination of difficulties for the diagnosis and treatment.Objective: to update and systematize knowledge about a devastating disease that is a challenge for surgeons.
Method: a review of the literature from the last five years was made. Six original articles, nine case reports and seven bibliographic reviews were included. There was particular attention to classification, pathogeny, diagnosis and treatment.
Development: necrotizing fasciiatis is an uncommon, progressive, deadly infection that can affect any part of the body but it is more frequent in extremities, especially the legs. It is mostly polimicrobial and affects the superficial fascia, the subcutaneous tissue, the subcutaneous fat with nerves, arteries, veins and the deep fascia. The infection progresses rapidly in few days. Microbiology, radiography and magnetic resonance imaging are the most used complementary studies. The diagnosis is mainly clinical. The treatment includes support hemodynamic measures, an extensive early surgical debridement and the use of antimicrobials, besides the general care.
Conclusions: necrotizing fasciiatis is an uncommon but potentially deadly disease that can affect any part of the organism. A great level of suspicion is needed due to the pause of the specific cutaneous manifestations. The antecedents and the clinical manifestations are key elements for the diagnosis. Immediate aggressive surgery is compulsory. In spite of all the measures taken, mortality is really high.
REFERENCES
Nazerani S, Maghari A, Kalantar Motamedi MH, Ardakani JV, Rashidian N, Nazerani T. Necrotiz-ing Fasciitis of the Upper Extremity, Case Re-port and Review of the Literature. Trauma Mon [Internet]. 2012 Summer [citado 26 Mar 2015];17(2):[aprox. 3 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860632 /
Changchien CH, Chen YY, Chen SW, Chen wL, Tsay JG, Chu C. Retrospective study of ne-crotizing fasciitis and characterization of its as-sociated Methicillin-resistant Staphylococcus aureus in Taiwan. BMC Infect Dis [Internet]. 2011 Oct [citado 26 Mar 2015];11(2):[aprox. 1 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221646/
Roje Z, Roje Z, Matiæ D, Librenjak D, Doku-zoviæ S, Varvodiæ J. Necrotizing fasciitis: litera-ture review of contemporary strategies for diag-nosing and management with three case re-ports: torso, abdominal wall, upper and lower limbs. World J Emerg Surg [Internet]. 2011 Dec [citado 26 Mar 2015];6:[aprox. 3 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310784/
Nae Yu S, Hyong Kim T, Jung Lee E, Choo EJ, Hyok Jeon M, Gyu Jung Y, et al. Necrotizing fasciitis in three University Hospitals in Korea: A change in causative Microorganisms and risk factors of mortality during the last decade. In-fect Chemother [Internet]. 2013 Dec [citado 26 Mar 2015];45(4):[aprox. 6 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902814/
Hakkarainen TW, Kopari NM, Pham TM, Evans HL. Necrotizing soft tissue infections: Review and current concepts in treatment, systems of care, and outcomes. Curr Probl Surg [Internet]. 2014 Aug [citado 26 Mar 2015];51(8):[aprox. 18 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199388/
Naqvi GA, Malik SA, Jan W. Necrotizing Fasciitis of the lower extremity: a case report and current concept of diagnosis and manage-ment. Scand J Trauma Resusc Emerg Med [Internet]. 2009 Jun [citado 26 Mar 2015];17(1):[aprox. 18 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704167/
Rimawi BH, Garybill W, Pierce JY, Kohler M, Eriksson EA, Sharvy MT, et al. Necrotizing Fasciitis and Toxic Shock Syndrome from Clos-tridium septicum following a Term Cesarean De-livery. Case Rep Obstet Gynecol [Internet]. 2014 Apr [citado 26 Mar 2015];2014(2014):[aprox. 5 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/PMC4005143/
Ju Zhao G, Liang Hong G, Quan Liu J, Qiu Lu Z. Septic shock due to community-acquired Pseudomonas aeruginosa necrotizing fasciitis: A case report and literature review. Exp Ther Med [Internet]. 2014 Jun [citado 6 Mar 2015];7(6):[aprox. 3 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043593/
Kumar Das D, Baker MG, Venugopal K. Risk factors, microbiological findings and outcomes of necrotizing fasciitis in New Zealand: a retro-spective chart review. Ann Surg [Internet]. 2012 Dec [citado 26 Mar 2015];12(12):[aprox. 11 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538518/
Kao LS, Lew DF, Arab SN, Todd SR, Awad SS, Carrick MM, et al. Local Variations in the Epide-miology, Microbiology, and Outcome of Necrotizing Soft Tissue Infections: A Multi-Center Study. Am J Surg [Internet]. 2011 Aug [citado 26 Mar 2015];202(2):[aprox. 6 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/ pmc/articles /PMC3150284/
Bisarya K, Azzopardi S, Lye G, Drew PJ. Ne-crotizing Fasciitis Versus Pyoderma Gangreno-sum: Securing the Correct Diagnosis! A Case Report and Literature Review. Eplasty [Internet]. 2011 May [citado 26 Mar 2015];11(5):[aprox. 7 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3097992/
Sinha N, Niazi M, Lvovsky D. A Fatal Case of Multidrug Resistant Acinetobacter Necrotizing Fasciitis: The Changing Scary Face of Noso-comial Infection. Case Rep Infect Dis [Internet]. 2013 Oct [citado 26 Mar 2015];2014(1):[aprox. 8 p.]. Disponible en:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202280/
Magala J, Makobore P, Makumbi T, Kaggwa S, Kalanzi E, Galukande M. The clinical presen-tation and early outcomes of necrotizing fasciit-is in a Ugandan Tertiary Hospital- a prospective study. BMC Res Notes [Internet]. 2014 Jul [citado 26 Mar 2015];7(7):[aprox. 8 p.]. Dis-ponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419938/
Alsharari M, Pasquesoone L, Khater R, Guerreschi P. De Broucker V, Duquennoy VM. Necrotizing soft tissue infections following a scald burn of the lower limb: a case report. Ann Burns Fire Disasters [Internet]. 2013 Sep [citado 26 Mar 2015];26(3):[aprox. 3 p.]. Dis-ponible en: http://www.ncbi.nlm.nih.gov/pmc/articles PMC3917152/
Khamnuan P, Chongruksut W, Jearwattanaka-nok K, Patumanond J, Yodluangfun S, Tantra-worasin A. Necrotizing fasciitis: risk factors of mortality. Risk Manag Healthc Policy [Internet]. 2015 Feb [citado 26 Mar 2015];2015(8):[aprox.7 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337692/
Yong Lee J, Jung H, Kwon H, No Jung S. Ex-tended negative pressure wound therapy-assisted dermatotraction for the closure of large open fasciotomy wounds in necrotizing fasciitis patients. World J Emerg Surg [Internet]. 2014 Apr [citado 26 Mar 2015];9(4):[aprox. 3 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996171/
Kwak BO, Jung Lee M, Won Park H, Kyung Song M, Chung S, Sun Kim K. Necrotizing fasciitis and streptococcal toxic shock syn-drome secondary to varicella in a healthy child. Korean J Pediatr [Internet]. 2014 Dec [citado 26 Mar 2015];57(12):[aprox.3 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316598/
Rausch J, Foca M. Necrotizing Fasciitis in a Pediatric Patient Caused by Lancefield Group G Streptococcus: Case Report and Brief Review of the Literature. Case Rep Med [Internet]. 2011 Dec [citado 26 Mar 2015];2011(2011):[aprox. 3 p.]. Disponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3254238/