2015, Number 12
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Ginecol Obstet Mex 2015; 83 (12)
Obstetric management in patients with severe pulmonary hypertension
Castillo-Luna R, Miranda-Araujo O
Language: Spanish
References: 32
Page: 785-797
PDF size: 454.95 Kb.
ABSTRACT
Background: Pulmonary hypertension is a disease of poor prognosis when is associated with pregnancy. A maternal mortality of 30-56% and a neonatal survival of approximately 85% is reported. Surveillance of patients with severe pulmonary hypertension during pregnancy must be multidisciplinary, to provide information and optimal treatment during and after gestation. Targeted therapy for pulmonary arterial hypertension during pregnancy significantly reduces mortality. The critical period with respect to mortality, is the first month after birth.
Objective: Propose an algorithm for management during pregnancy for patients with severe pulmonary hypertension who want to continue with it.
Conclusions: The recommendations established with clinical evidence for patients with severe pulmonary hypertension and pregnancy are presented: diagnosis, treatment, obstetrics and cardiology management, preoperative recommendations for termination of pregnancy, post-partum care and contraception. The maternal mortality remains significantly higher in patients with severe pulmonary hypertension and pregnancy, in these cases should be performed multidisciplinary management in hospitals that have experience in the management of this disease and its complications.
REFERENCES
Bassily-Marcus A, Yuan C, Oropello J, Manasia A, et al. Pulmonary hypertension in pregnancy: critical care management. Pulmon Med 2012;2012:1-9.
Weiss B, Zemp L, Seifert B, et al. Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996. J Am Coll Cardiol 1998;31:1650-1657.
Bedard E, Dimopoulos K, Gatzoulis M. Has there been any progress made on pregnancy outcomes among women with pulmonary artery hypertension. Eur Heart J 2009;30:256-265.
Smith J, Mueller J, Daniels C. Pulmonary arterial hypertension in the setting of pregnancy: a case series and standard treatment approach. Lung 2012;190:155-160.
Galié N, Hoeper M, Humbert M, et al. For: The Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J 2009;30:2493-2537.
Simonneau G, Galiè N, Rubin L, et al. Clinical classification of pulmonary arterial hypertension. J Am Coll Cardiol 2004;43:S5-S12.
Simonneau G, Robbins IM, Beghetti M, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2009;54:S43-S54.
Gei A, Montúfar-Rueda C. Pulmonary hypertension and pregnancy: an overview. Clin Obstet Gynecol 2014;57:806-826.
Hoeper M, Bogaard H, Condliffe R, et al. Definitions and diagnosis of pulmonary hypertension. J Am Coll Cardiol 2013;62:D42-D50.
Fisher M, Forfia P, Chamera E, et al. Accuracy of doppler echocardiography in the hemodynamic assessment of pulmonary hypertension. Am J Respir Crit Care Med 2009;179:615-621.
Ouzounian J, Elkayam U. Physiologic Changes during normal pregnancy and delivery. Cardiol Clin 2012;30:317-329.
Pijuan A, Gatzoulis M. Embarazo y cardiopatía. Rev Esp Cardiol 2006; 59:971-84.
Avellana P, Segovia J, López F, et al. Hipertensión pulmonar y embarazo. Doyma Elsevier 2011;22:1-8.
Manso B, Gran F, Pijuán A, et al. Embarazo y cardiopatías congénitas. Rev Esp Cardiol 2008;61:236-243.
CENETEC. Diagnóstico y manejo de la Cardiopatia en el embarazo. México; Secretaría de Salud, 2011.
Warnes C, Williams R, Bashore T, et al. ACC/AHA 2008 Guidelines for the management of adults with congenital heart disease. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. JACC 2008;52:143-263.
Cueto G, Mares Y, De la Escosura G, et al. Diagnóstico de la hipertensión pulmonar. Rev Inst Nal Enf Resp Mex 2004;17:S28-S39.
Barberá J, Escribano P, Morales P, et al. Standards of care in pulmonary hypertension. Rev Esp Cardiol 2008;61:170-184.
Cartago R, Ann P, Benedicto J. Pregnancy outcomes in patients with severe pulmonary hypertension and Eisenmenger syndrome treated with sildenafil monotherapy. Obstetric Med 2014;7:40-42.
Weiss B, Hess O. Pulmonary vascular disease and pregnancy: current controversies, management strategies, and perspectives. Eur Heart J 2000;21:104-115.
Kiely D, Condliffe R, Webster V, et al. Improved survival in pregnancy and pulmonary hypertension using a multiprofessional approach. BJOG 2010;117:565-574.
Sociedad Argentina de Cardiología (SAC), Asociación Argentina de Medicina Respiratoria (AAMR), Sociedad Argentina de Reumatología (SAR). Consenso para el diagnóstico y tratamiento de la hipertensión arterial pulmonar. Rev Arg Cardiol 2011;79:1-32.
McLaughlin V, Archer S, Badesch D, et al. ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension. A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association (AHA). JACC 2009;53:1573-1619.
Pieper P, Lameijer H, Hoendermis E. Pregnancy and pulmonary hypertension. Best Pract Res Clin Obstet Gynaecol 2014;28:579-591.
Rosengarten D, Kramer M. Pregnancy in pulmonary arterial hypertension patients. Harefuah 2013;152:547-51.
Elliot C, Stewart P, Webster V, et al. The use of Iloprost in early pregnancy in patients with pulmonary artery hypertension. Eur Respir J 2005;26:168-173.
Pieper P, Hoendermis E. Pregnancy in women with pulmonary hypertension. Neth Heart J 2011;19:504-508.
Lane R, Trow T. Pregnancy and pulmonary hypertension. Clin Chest Med 2011;3:165-74.
Bonet-Carne E, Palacio M, Cobo T, et al. Quantitative ultrasound texture analysis of fetal lungs to predict neonatal respiratory morbidity. Ultrasound Obstet Gynecol 2015;45:427-33.
Davies G, Herbert W. Assessment and management of cardiac disease in pregnancy. J Obstet Gynaecol Can 2007;29:331-336.
Viktorsdottir O. Pulmonary hypertension in pregnancy and anesthetic implications. Curr Anesthesiol Rep 2015;5:82-90.
Bonnin M, Mercier F, Sitbon O, et al. Severe pulmonary hypertension during pregnancy: mode of delivery and anesthetic management of 15 consecutive cases. Anesthesiology 2005;102:1133-1137.