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2015, Number 3

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Residente 2015; 10 (3)

Sobre el tratamiento de la enfermedad pulmonar intersticial en artritis reumatoide

Ponce-Campos SD, Martín-Márquez BT, Chávez-García D, Olvera-Palafox CN, Cardona-Müller D, Ponce-Muñoz M, Díaz-Rizo V, González-López L

Language: Spanish
References: 45
Page: 132-141
PDF size: 236.90 Kb.


ABSTRACT

Rheumatoid arthritis (AR) is an inflammatory disease of the synovial joints that frequently presents with systemic manifestations. One expression of this extra-articular disease with greater impact on mortality is the interstitial lung disease (ILD). The ILD can occur in clinical rheumatology affecting about 3-4% percent of the patients with RA, but survival is significantly affected, especially in patients with severe disease: it can be two to three years after their diagnosis. Early diagnosis of this complication is very important in order to initiate a multidisciplinary treatment. Chest radiographs are of low utility in establishing the diagnosis in the early stages of the disease because they offer low sensitivity and abnormal data reveal only severe illness or late stages; therefore, a comprehensive diagnostic approach involving specialists in internal medicine, pulmonology, rheumatology and cardiology should be considered in patients with suspected EPI; this initial approach requires lung function tests and computed tomography high resolution. This review describes the epidemiology and etiological factors related to the development of this entity, as well as its clinical features, diagnostic evaluation methods and evidence regarding the treatments used for ILD, including corticosteroids, immunosuppressants and biological agents.


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