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2015, Number 1

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Invest Medicoquir 2015; 7 (1)

Relationship between carotid intima-media thickness, cardiovascular risk factors, and coronary artery diseases

Pérez BA, Muñoz ÁJ, Ravelo LK, Abreu CA, Puig FMJ, Aldama PL

Language: Spanish
References: 47
Page: 4-27
PDF size: 245.66 Kb.


ABSTRACT

Introduction: Cardiovascular diseases are the first cause of death in Cuba. Ischemic cardiopathies are part of this group; the myocardial infarctions represent one third of the total of these causes of death, 95 % of coronary artery disease has its origin in the atherosclerosis. Once we can identify those people who suffer from subclinic atherosclerosis, we will be able to revert statistics. An observational, prospective, and analytical study was carried out, with the main goal of assessing the relationship among CIMT (Carotid intima-media thickness), cardiovascular risk factors, and coronary artery disease prevalence. Methods: The sample had a total of 72 patients, who underwent CIMT and coronariography exams. Sex, age, coronary risk factors, the coronariography outcomes analysing if significant coronary illnesses existed or not, number, and kind of the affected artery. In addition, the CIMT medium values of both carotid arteries were studied. A database for statistical processing was designed. Results: Proportional relationship between CIMT and hypertension, hipercholesterolemy, age, sex, and coronary lesions (without being related to the number or kind of artery) was found. The study offered a sensibility of 75.5 % and a specificity of 71.4 %, with a positive predictive value of 86% for the coronary artery disease diagnosis. Conclusion: CIMT is a valuable tool predicting coronary artery diseases.


REFERENCES

  1. Myocardial infraction redefined a consensus document of The Joint European Society of Cardiology. American College of Cardiology Committee for the redefinition of myocardial infarction. Eur Heart J. 2000;21(18):1502-13.

  2. European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens. 2003;21(6):1011-53.

  3. Anuario estadístico de salud. Ministerio de Salud Pública. Cuba. 2009;20(3):9 (Consultado en noviembre de 2010). Disponible en: URL: http://bvs.sld.cu/revistas/end/vol20_3_09/end01309.pdf

  4. Fernández JE. Atherosclerotic lesion: a morphometric study appying a biometric system. Thesis of Doctor in Medical Sciences. Berlin, Humboldt University; 1987. p. 48.

  5. Bauer M, Möhlenkamp S, Lehmann N, Schmermund A, Roggenbuck U, Moebus S, et al. The effect of age and risk factors on coronary and carotid artery atherosclerotic burden in males. Results of the Heinz Nixdorf Recall Study. Atheroscler. 2009;205(2):595-602.

  6. Kagan AR. Atherosclerosis. WHO study on atherosclerosis of the aorta and coronary arteries. Chronics of the WHO. 1977;31(9):187-97.

  7. Stein HJ, Mathiesen EB. Carotid plaque compared with intima media thickness as a predictor of coronary and cerebrovascular diseas. Current Cardiol Rep. 2009;11(4):21-7.

  8. Mok CC, Poon WL, Lai JP, Wong CK, Chiu SM, Wong CK, et al. Metabolic syndrome, endothelial injury, and subclinical atherosclerosis in patients with systemic lupus erythematosus. Scand J Rheumatol. 2010;39(1):42-9.

  9. Tzou WS, Douglas PS, Srinivasan SR, Bond MG, Tang R, Chen W, et al. Increased subclinical atherosclerosis in young adults with metabolic syndrome: the Bogalusa Heart Study. J Am Coll Cardiol. 2005;46(3):457-63.

  10. Stein JH, Korcarz CE, Hurst RT, Lonn E, Kendall CB, Mohler ER, et al. American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Use of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task Force. Endorsed by the Society for Vascular Medicine. J Am Soc Echocardiogr. 2008;21(2):93-111.

  11. Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulat. 1986;74(11):1399-1406.

  12. Mark DB, Shaw LJ, Lauer MS, O’Malley PG, Heidenreich P. 34th Bethesda Conference: Task Force 5 ¿Is atherosclerosis imaging cost effective? J Am Coll Cardiol. 2003;41(6):1906-17.

  13. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulat. 2002;106(36):3143-421.

  14. Sinha AK, Eigenbrodt M, Mehta JL. Does carotid intima media thickness indicate coronary atherosclerosis? Curr Opin Cardiol. 2002;17(5):526-30.

  15. Bond MG, Barnes RW, Riley WA, Wilmoth SK. High resolution B-mode ultrasound scanning methods in communities study (ARIC). J Neuroimag. 1991;1(2):68-72.

  16. Sakaguchi M, Kitagawa K, Nagai Y, Yamagami H, Kondo K, Matsushita K, et al. Equivalence of plaque score and intima-media thickness of carotid ultrasonography for predicting severe coronary artery lesion. Ultrasound Med Biol. 2003;29(3):367-71.

  17. Smith SC Jr, Allen J, Blair SN, Bonow RO, Brass LM, Fonarow GC, et al. AHA/ACC National Heart, Lung, and Blood Institute. AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute. Circulat. 2006;113(14):2363-72.

  18. Holland Z, Ntyintyane L, Gill G, Raal F. Carotid intima-media thickness is a predictor of coronary artery disease in South African black patients. Cardiovasc J Afr. 2009;20(4):237-9.

  19. Johnsen SH, Mathiesen EB. Carotid plaque compared with intima-media thickness as a predictor of coronary and cerebrovascular disease. Curr Cardiol Rep. 2009;11(1):21-7.

  20. Touboul P, Hennerici MG, Meairs S, Adams H, Amarenco P, Bornstein N, et al. Mannheim Carotid Intima-Media Thickness Consensus (2004–2006). Cerebrovasc Dis. 2007;23(9):75-80.

  21. Heuten H, Goovaerts I, Ennekens G, Vrints C. Carotid artery intima-media thickness is associated with coronary artery disease. Acta Cardiol. 2008;63(3):309-13.

  22. Chambless LE, Heiss G, Folsom AR, Rosamond W, Szklo M, Sharrett AR, et al. Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the atherosclerosis risk in communities (ARIC) study, 1987-1993. Am J Epidemiol. 1997;146(17):483-94.

  23. O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med. 1999;340(46):14-22.

  24. Naghavi M, Falk E, Hecht HS, Jamieson MJ, Kaul S, Berman D, et al. SHAPE Task Force. From vulnerable plaque to vulnerable patient-part III: executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report. Am J Cardiol. 2006;98(21):2-15.

  25. Hertzer NR, Young JR, Bevent G, Graor RA, O'Hara PJ, Ruschhaupt WF, et al. Coronary angiography in 506 patients with extracranial cerebrovascular disease. Arch Intern Med. 1985;45(20):849-85.

  26. Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam study. Circulat. 1997;96(30):1432-7.

  27. Van der Meer IM, Bots ML, Hofman A, del Sol AI, van der Kuip DA, Witteman JC. Predictive value of noninvasive measures of atherosclerosis for incident myocardial infarction: the Rotterdam study. Circulat. 2004;109(25):1089-94.

  28. Urbina EM, Srinivasan SR, Tang R, Bond MG, Kieltyka L, Berenson GS. Bogalusa Heart Study. Impact of multiple coronary risk factors on the intima-media thickness of different segments of carotid artery in healthy young adults (the Bogalusa Heart Study). Am J Cardiol. 2002;90(19):953-8.

  29. D’Agostino RB, Burke G, O’Leary D, Rewers M, Selby J, Savage PJ, et al. Ethnic differences in carotid wall thickness: the Insulin Resistance Atherosclerosis Study. Stroke. 1996;27(8):1744-9.

  30. Yildiz S, Yildiz A, Ertug N, Kaya I, Yilmaz R, Yuksel E, et al. Association of breast arterial calcification and carotid intima-media thickness. Heart Vessels. 2008;23(6):376-82.

  31. Baroncini LA, de Oliveira A, Vidal EA, França GJ, Stahlke PS, Alessi A, et al. Appropriateness of carotid plaque and intima-media thickness assessment in routine clinical practice. Cardiovasc Ultrasound. 2008;16(6):52.

  32. Meriño E, Hierro D, Herrera A, Nasiff A. Utilidad de asociación de factores de riesgo cardiovasculares y aterosclerosis carotidea en el diagnóstico de cardiopatía isquémica. Rev. Cub. Med. 2005;44(3-4):43-405 (Consultado en noviembre de 2010). Disponible en: URL: http://scielo.sld.cu/pdf/med/v44n3-4/med043-405.pdf.

  33. Kostandonis D, Papadopoulos V, Toumanidis S, Papamichael C, Kanakakis I, Zakopoulos N. Topography and severity of coronary artery disease in white-coat hypertension. Eur J Intern Med. 2008;19(4):280-4.

  34. Meijs MF, Doevendans PA, Cramer MJ, Vonken EJ, Velthuis BK, van der Graaf Y, et al. Relation of common carotid intima-media thickness with left ventricular mass caused by shared risk factors for hypertrophy. J Am Soc Echocardiogr. 2009;22(5):499-504.

  35. Kornet L, Lambregts J, Hoeks AP, Reneman RS. Differences in near-wall shear rate in the carotid artery within subjects are associated with different intima-media thicknesses. Arterioscler Thromb Vasc Biol. 1998;18(6):1877-84.

  36. Dalager S, Paaske WP, Kristensen IB, Laurberg JM, Falk E. Artery-related differences in atherosclerosis expression: implications for atherogenesis and dynamics in intima-media thickness. Stroke. 2007;38(13):2698-2705.

  37. Taylor AJ, Kent SM, Flaherty PJ, Coyle LC, Markwood TT, Vernalis MN. ARBITER: arterial biology for the investigation of the treatment effects of reducing cholesterol a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness. Circulat. 2002;106(37):2055-60.

  38. Haukkamaa L, Moilanen L, Kattainen A, Luoto R, Kahonen M, Leinonen M, et al. Pre-eclampsia is a risk factor of carotid artery atherosclerosis. Cerebrovasc Dis. 2009;27(6):599-607.

  39. Alaee A, Khademloo M. Evaluation of correlation between carotid artery intima media wall thickness and coronary artery stenosis in Sari, north of Iran. Pak J Biol Sci. 2008;11(19):2360-3.

  40. Cicorella N, Zanolla L, Franceschini L, Cacici G, De Cristan B, Arieti M. Usefulness of ultrasonographic markers of carotid atherosclerosis (intima-mediathickness, unstable carotid plaques and severe carotid stenosis) for predicting presence and extent of coronary artery disease. Hagerstown. J Cardiovasc Med. 2009;10(12):906-12.

  41. Demircan S, Tekin A, Tekin G, Topcu S, Yigit F, Erol T, et al. Comparison of carotid intima-media thickness in patients with stable angina pectoris versus patients with acute coronary syndrome. Am J Cardiol. 2005;96(24):643-4.

  42. Camsari A, Ozcan T, Ozer C, Akcay B. Carotid artery intima-media thickness correlates with intravascular ultrasound parameters in patients with slow coronary flow. Atheroscler. 2008;200(2):310-4.

  43. Hodis HN, Mack WJ, LaBree L, Selzer RH, Liu CR, Liu CH, et al. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med. 1998;128(46):262-9.

  44. Yu C-M, Zhang Q, Lam L, Lin H, Kong SL, Chan W, et al. Comparison of intensive and low-dose atorvastatin therapy in the reduction of carotid intimal-medial thickness in patients with coronary heart disease. Heart. 2007;93(23):933-9.

  45. Djaberi R, Schuijf JD, de Koning EJ, Rabelink TJ, Smit JW, Kroft LJ, et al. Usefulness of carotid intima-media thickness in patients with diabetes mellitus as a predictor of coronary artery disease. Am J Cardiol. 2009;104(8):1041-6.

  46. Yasuda T, Matsuhisa M, Fujiki N, Sakamoto F, Tsuji M, Fujisawa N, et al. Is central obesity a good predictor of carotid atherosclerosis in Japanese type 2 diabetes with metabolic syndrome? Endocr J. 2007;54(5):695-702.

  47. Simova I, Denchev S. Endothelial functional and structural impairment in patients with different degrees of coronary artery disease development. Heart Vessels. 2008;23(5):308-15.




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