2015, Number 2
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Rev Clin Esc Med 2015; 5 (2)
Cryptogenic organizing pneumonia
Sibaja CM, Monge BC
Language: English
References: 33
Page: 11-16
PDF size: 349.30 Kb.
ABSTRACT
Cryptogenic organizing pneumonia (COP) is a
distinct histopathologic entity characterized by
Masson bodies which are intraalveolar buds of
granulation tissue; consisting of connective
tissue and myofibroblasts. This pathologic pattern
when present with the characteristic imaging
and clinical features of COP defines the
diagnosis of the disease. A specific etiology is
not found. Treatment with corticosteroids results
in a rapid clinical and imaging improvement
but unfortunately relapses are common
upon decreasing the dose or stopping the treatment.
This case report describes a typical case
of COP with the characteristic improvement
with corticosteroid therapy and relapse upon
treatment taper
REFERENCES
Cordier JF. Cryptogenic organising pneumonia. Eur Respir J. 2006;28:422.
Epler GR. Bronchiolitis obliterans organizing pneumonia. Arch Intern Med 2001;161:158.
Ryu JH Myers JL Swensen SJ. Bronchiolar disorders. Am J Respir Crit Care Med. 2003;168:1277.
Lohr RH Boland BJ Douglas WW et al. Organizing pneumonia. Features and prognosis of cryptogenic, secondary and focal variants. Arch Intern Med. 1997;157:1323-1329.
Alasaly K Muller N Ostrow DN et al. Cryptogenic organizing pneumonia. A report of 25 cases and a review of the literature. Medicine (Baltimore). 1995; 74:201.
Gudmundsson G Sveinsson O Isaksson HJ et al. Epidemiology of organising pneumonia in Iceland. Thorax 2006; 61:805.
Peyrol S Cordier JF Grimaud JA. Intra- alveolar fibrosis of idiopathic bronchiolitis obliterans-organizing pneumonia. Cell-matrix patterns. Am J Pathol. 1990;137:155-170.
Takiya C Peyrol S Cordier JF Grimaud JA. Connective matrix organization in human pulmonary firbosis. Collagen polymorphism analysis in fibrotic deposit by immunohistological methods. Virchows Arch. 1983;44:223-240.
Kuhn C 3rd Boldt J King TE Crouch E Vartio T McDonald JA. An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis. Am Rev Respir Dis. 1989;140:1693-1703.
Lappi-Blanco E Kaarteenaho-Wiik R Soini Y Risteli J Paakko P. Intraluminal fibromyxoid lesions in bronchiolitis obliterans organizing pneumonia are highly capillarized. Hum Pathol. 1999;30:1192–1196.
Lappi-Blanco E Soini Y Kinnula V Paakko P. VEGF and bFGF are highly expressed in intraluminal fibromyxoid lesions in bronchiolitis obliterans organizing pneumonia. J Pathol 2002; 196:220–227.
Mroz BJ Sexauer WP Meade A Balsara G. Hemoptysis as the presenting symptom in bronchiolitis obliterans organizing pneumonia. Chest. 1997; 111:1775–1778.
Yang DG Kim KD Shin DH Choe KO Kim SK Lee WY. Idiopathic bronchiolitis obliterans with organizing pneumonia presenting with spontaneous hydropneumothorax and solitary pulmonary nodule. Respirology. 1999; 4: 267–270.
Johkoh T, Muller NL, Cartier Y, et al. Idiopathic interstitial pneumonias: diagnostic accuracy of thin- section CT in 129 patients. Radiology. 1999;211: 555–560.
Carrington C Addington W Goff A Madoff I Marks A Schwaber J. Chronic eosinophilic pneumonia. N Engl J Med. 1969;280:787–798.
Costabel U Teschler H Schoenfeld B et al. BOOP in Europe. Chest. 1992;102: (Suppl.1):14S–20S.
Bellomo R Finlay M McLaughlin P Tai E. Clinical spectrum of cryptogenic organizing pneumonitis. Thorax. 1991; 46:554–558.
Costabel U Teschler H Guzman J. Bronchiolitis obliterans organizing pneumonia (BOOP): the cytological and immunocytological profile of bronchoalveolar lavage. Eur Respir J. 1992;5:791–797.
Poletti V Cazzato S Minicuci N Zompatori M Burzi M Schiattone ML. The diagnostic value of broncho- alveolar lavage and transbronchial lung biopsy in cryptogenic organizing pneumonia. Eur Respir J. 1996;9:2513–2516.
Nagai S Aung H Tanaka S et al. Bronchoalveolar lavage cell findings in patients with BOOP and related diseases. Chest. 1992;102: (Suppl. 1):32S–37S.
Colby TV. Pathologic aspects of bronchiolitis obliterans organizing pneumonia. Chest. 1992;102(Suppl. 1): 38S–43S.
Kitaichi M. Differential diagnosis of bronchiolitis obliterans organizing pneumonia. Chest. 1992;102:(Suppl. 1):44S–49S.
Basset F Ferrans VJ Soler P Takemura T Fukuda Y Crystal RG. Intraluminal fibrosis in interstitial lung disorders. Am J Pathol. 1986;122: 443–461.
King TE Jr. Organizing pneumonia. In: Interstitial lung disease, 5, Schwarz MI, King TE Jr. (Eds), People's Medical Publishing House, Shelton, CT 2011. p.981.
Oymak FS Demirbaş HM Mavili E et al. Bronchiolitis obliterans organizing pneumonia. Clinical and roentgenological features in 26 cases. Respiration. 2005;72:254.
Bradley B Branley HM Egan JJ et al. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax. 2008;63 Suppl 5:v1.
Lazor R Vandevenne A Pelletier A et al. Cryptogenic organizing pneumonia. Characteristics of relapses in a series of 48 patients. The Groupe d'Etudes et de Recherche sur les Maladles "Orphelines" Pulmonaires (GERM"O"P). Am J Respir Crit Care Med. 2000;162:571.
Nizami IY Kissner DG Visscher DW Dubaybo BA. Idiopathic bronchiolitis obliterans with organizing pneumonia. An acute and life-threatening syndrome. Chest. 1995;108:271.
Pérez de Llano LA Soilán JL García Pais MJ et al. Idiopathic bronchiolitis obliterans with organizing pneumonia presenting with adult respiratory distress syndrome. Respir Med. 1998; 92: 884.
Purcell IF Bourke SJ Marshall SM. Cyclophosphamide in severe steroidresistant bronchiolitis obliterans organizing pneumonia. Respir Med 1997; 91:175.
Ning-Sheng L Chun-Liang L Ray- Sheng L. Bronchiolitis obliterans organizing pneumonia in a patient with Behçet's disease. Scand J Rheumatol. 2004;33:437.
Lee YH Choi SJ Ji JD et al. Dermatomyositis without elevation of creatine kinase presented as bronchiolitis obliterans organizing pneumonia. Korean J Intern Med. 2000;15:85.
Laszlo A Espolio Y Auckenthaler A et al. Azathioprine and low-dose corticosteroids for the treatment of cryptogenic organizing pneumonia in an older patient. J Am Geriatr Soc. 2003;51: 433.