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2005, Number 1

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Acta Pediatr Mex 2005; 26 (1)

Cryptococosis. Natural history and present state of its treatment

Vázquez TO, Martínez BI, Campos RT

Language: Spanish
References: 41
Page: 18-28
PDF size: 76.06 Kb.


ABSTRACT

Cryptococosis is a severe opportunistic mycotic disease caused by Cryotococcus neoformans, an encapsulated, yeast-like fungus. The two varieties Cryptococcus neoformans var. neoformans (serotypes A and D) and Cryptococcus neoformans var. gatti (serotypes B and C) are responsible for human disease. It occurs by inhalation of the microorganism present mainly in pigeon’s stools. It causes a pulmonary infection and disseminates to other organs, meninges and central nervous system causing meningoencephalitis; it can also affect skin and other viscera. Cryptococosis affects immunosupressed patients, especially patients with AIDS. This paper reviews the present state of the disease with special attention to the clinical features, diagnostic approach and treatment.


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