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2015, Number 4

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Rev Cub Med Int Emerg 2015; 14 (4)

Breathing difficulty as the initial manifestation of pseudohypoaldosteronism in neonate

Boni LE, Fortini YV

Language: Spanish
References: 10
Page: 76-81
PDF size: 385.19 Kb.


ABSTRACT

The pseudohypoaldosteronism (PHA) is a rare genetic disease in the childhood characterized by hydrosaline loss and hyperkalemia associated with abnormally high levels of renin and aldosterone. It is caused by an alteration in the aldosterone receptor that produces an inadequate response even at high levels of it. The case of an infant who was admitted with symptoms of respiratory distress associated with hyponatremia and severe hyperkalemia with elevated 17-hydroxy-progesterone, renin and aldosterone. This disease presents the main differential diagnosis of congenital adrenal hyperplasia with similar electrolyte abnormalities, making it difficult to recognize at first instance.


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