2015, Number 4
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Med Int Mex 2015; 31 (4)
Prevalence of proteinuria and persistent proteinuria in young students from a high school in Hidalgo, Mexico
López-López E, López-Carbajal MJ, Ortiz-Gress AA
Language: Spanish
References: 25
Page: 374-379
PDF size: 397.35 Kb.
ABSTRACT
Background: Proteinuria is common in children, it can be benign or a severe systemic disorder. Persistent proteinuria accelerates the decline of glomerular filtration rate and is key in the progression of chronic renal disease.
Objective: To identify the prevalence of proteinuria and persistent proteinuria in the young population of senior high school and its association with blood pressure and body mass index.
Population and method: A descriptive cross-sectional study was done with young people from St. Augustine Tlaxiaca, Hidalgo, Mexico, in 2014. Initially, the prevalence was determined using dipstick, weight, height, systolic and diastolic blood pressure was taken. The second stage evaluated the same variables again and finally who were positive in one or both phases to proteinuria, it was considered persistent proteinuria.
Results: The prevalence of proteinuria was 11%, 64% were female and 17% were obese, the mean age was 16.6±1.3 years. The mean systolic and diastolic blood pressure in those who had proteinuria was 104.6±13.69 mmHg and 61.6±9.4 mmHg, respectively. The prevalence of persistent proteinuria was 4%.
Conclusions: The prevalence of proteinuria and persistent proteinuria was higher in this group compared to that reported in other studies with similar population. It was not associated with BMI and blood pressure. It may not be manifested because the damage is mild.
REFERENCES
Halbesma N, Kuiken DS, Brantsma AH, Bakker SJ, et al. Macroalbuminuria is a better risk marker tan low estimated GFR to identify individuals at risk for accelerated GFR loss in population screening. J Am Soc Nephrol 2006;17:2582-2590.
Tsao YC, Chan WC, Gibson JB. Persistent proteinuria in children. Arch Dis Child 1969;44:443-453.
Leung AK, Wong AH. Proteinuria in children. Am Fam Physician 2010;82:645-651.
Tryggvason K, Pettersson E. Causes and consequences of proteinuria: the kidney filtration barrier and progressive renal failure. J Intern Med 2003;254:216-224.
Medeiros M, Muñoz Arizpe R. Enfermedad renal en niños. Un problema de salud pública. Bol Med Hosp Infant Mex 2011;68:259-261.
López-Cervantes M, Rojas-Russell ME, Tirado-Gómez LL, Durán-Arenas L, et al. Enfermedad renal crónica y su atención mediante tratamiento sustitutivo en México. México, DF: Facultad de Medicina, Universidad Nacional Autónoma de México, 2009.
Amato D, Álvarez-Aguilar C, Castaneda-Limones R, Rodriguez E, et al. Prevalence of chronic kidney disease in an urban Mexican population. Kidney Int Suppl 2005;68:S11-S17.
Cueto-Manzano AM, Rojas-Campos E. Status of renal replacement therapy and peritoneal dialysis in Mexico. Perit Dial Int 2007;27:142-148.
Glassock RJ. The rising tide of end-stage renal disease: what can be done? Clin Exp Nephrol 2004;8:291-296.
Plata R, Silva C, Yahuita J, Perez L, et al. The first clinical and epidemiological programme on renal disease in Bolivia: a model for prevention and early diagnosis of renal diseases in the developing countries. Nephrol Dial Transplant 1998;13:3034-3036.
Góngora-Ortega J, Serna-Vela FJ, Gutiérrez-Mendoza I, Pérez-Guzmán C y col. Prevalencia de enfermedad renal crónica en niños de Aguascalientes, México. Salud Pública Méx 2008;50:436-437.
Koshy SM, Garcia-Garcia G, Pamplona JS, Renoirte- Lopez K, et al. Screening for kidney disease in children on World Kidney Day in Jalisco, Mexico Pediatr Nephrol 2009;24:1219-1225.
Von Bonsdorff M, Koskenvuo K, Salmi HA, Pasternack A. Prevalence and causes of proteinuria in 20-year-old Finnish men. Scand J Urol Nephrol 1981;15:285-290.
Nagai K, Saito C, Watanabe F, Ohkubo R, et al. Annual incidence of persistent proteinuria in the general population from Ibaraki annual urinalysis study. Clin Exp Nephrol 2013;17:255-260.
Murakami M, Hayakawa M, Yanagihara T, Hukunaga Y. Proteinuria screening for children. Kidney Int 2005;67:S23-S27.
Cortes-Sanabria L, et al. Utility of the Dipstick Micraltest IITM in the screening of microalbuminuria of diabetes mellitus type 2 and essential hypertension. Rev Invest Clín 2006;58:190-197.
Cavalcante MA, Coelho SN, Lacerda HR. Prevalence of persistent proteinuria in stable HIV/AIDS patients and its association with HIV nephropathy. Braz J Infect Dis 2007;11:456-461.
Reich HN, Gladman DD, Urowitz MB, Bargman JM, et al. Persistent proteinuria and dyslipidemia increase the risk of progressive chronic kidney disease in lupus erythematosus. Kidney Int 2011;79:914-920.
Marsciani M, Pasini A, Montini G. Asymptomatic proteinuria in children. G Ital Nefrol 2011;28:489-498.
Kashif W, Siddiqi N, Dincer AP, Dincer HE, Hirsch S. Proteinuria: how to evaluate an important finding. Cleve Clin J Med 2003;70:535-537, 541-544, 546-547.
Wing MR, Yang W, T, et al., Chronic Renal Insufficiency Cohort (CRIC) Study. Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study. Obesity 2014;22:1359-1366.
Heathcote KL, Wilson MP, Quest DW, Wilson TW. Prevalence and duration of exercise induced albuminuria in healthy people. Clin Invest Med 2009;32:E261-5.
Mustafa A. Management of chronic kidney disease: A Clinician’s Guide. Turkey. Springer.
Hogg RJ. Screening for CKD in children: a global controversy. Clin J Am Soc Nephrol 2009;4:509-515.
Imai E, Yamagata K, Iseki K, Iso H, et al Kidney disease screening program in Japan: history, outcome, and perspectives Clin J Am Soc Nephrol 2007;2:1360-1366.