2015, Number 1
<< Back Next >>
Rev Cub Oftal 2015; 28 (1)
Electrophysiology of vision and generalization of normative studies in healthy individuals
Hernández EO, Columbié GYE, Hernández SY, Llanes RR, Castells FR, Ferro HD
Language: Spanish
References: 13
Page: 23-33
PDF size: 127.93 Kb.
ABSTRACT
Objective: to obtain normative data of standard and pattern electroretinography as
well as pattern and diffuse light visual evoked potentials from a group of healthy
individuals.
Methods: a prospective and descriptive study conducted in healthy subjects who
were seen at the neurophthalmology service in "Ramón Pando Ferrer" Cuban Institute
of Ophthalmology in a six-month period. Sixty eyes of adults aged 20-40 years of
both sexes with normal ophthalmologic physical examination results were included.
Results: mean values of amplitude and latency at the wave peak of P50 for the
pattern electroretinogram were 1,75 microvolts and 53,7 ms. The standard
electroretinogram showed b-wave amplitude values of 300, 550 and 290 microvolts
for scotopic, mesopic and photopic responses, respectively. The latency of the
P100 wave peak in pattern visual evoked potentials at 60 and 20 minutes of arc were
107 and 110 ms and at the diffuse light response, P-2 value was 110 ms with
interocular difference lower than 5 ms in both studies.
Conclusions: the suggested electrophysiological studies show normal useful values in
the evaluation of pathological findings indicative of visual functional impairment at
different levels and they may serve as a valid tool of reference for the rest of visual
electrophysiology laboratories located in the ophthalmological centers nationwide.
REFERENCES
Marmor MF, Fulton AB, Holder GE, Miyake Y, Brigell M. ISCEV Standard for full-field clinical electroretinography. Doc Ophthalmol. 2009;118:69-77.
Bach M, Brigell MG, Hawlina M, Holder GE, Johnson MA, McCulloch DL, et al. ISCEV standard for clinical pattern electroretinography. Doc Ophthalmol. 2013;126:1-7.
American Clinical Neurophysiology Society. Guideline 5: Guidelines for standard electrode position nomenclature. J Clin Neurophysiol. 2006;23:107. p. 10.
Catalá Mora J, Castany Aregoll M. Pruebas electrofisiológicas: ¿qué, cuándo, cómo y por qué? Ann Oftalmol. 2005;13(1):8-29.
Holder GE. Pattern electroretinography (PERG) and an integrated approach to visual pathway diagnosis. Prog Retin Eye Res. 2001;20:531-61.
Odom JV, Bach M, Bereber C. Visual evoked potentials standard. Doc Opthalmol. 2004;108:115-23.
Whatham AR, Nguyen V, Zhu Y, Hennessy M, Kalloniati M. The value of clinical electrophysiology in the assessment of the eye and visual system in the era of advanced imaging. Clin Exp Optom. 2014;97:99-115 DOI:10.1111/cxo.12085.
Parisi V, Miglior S, Manni G, et al. Clinical ability of pattern electroretinograms and visual evoked potentials in detecting visual dysfunction in ocular hypertension and glaucoma. Ophthalmology. 2006;113:216-28.
Ventura LM, Porciatti V, Ishida K, et al. Pattern electroretinogram abnormality and glaucoma. Ophthalmoly. 2005;112:10-9.
Lenassi E, Jarc-Vidmar M, Glavac D, Hawlina M. Pattern electroretinography of larger stimulus field size and spectral-domain optical coherence tomography in patients with Stargardt disease. Br J Ophthalmol. 2009;93:1605. doi:10.1136/bjo.2009.158725.
Jeon. Assessment of visual disability using visual evoked potentials. BMC Ophthalmol. 2012;12:36.
You Y, Klistorner A, Thie J, Graham SL. Latency delay of visual evoked potential is a real measurement of demyelination in a rat model of optic neuritis. Invest Ophthalmol Vis Sci. 2011;52(9):6911-8. doi: 10.1167/iovs.11-7434.
Kodama K. Standard and limitation of intraoperative monitoring of the visual evoked potential. Ac Neurochir. 2010;152(4):643-8.