2015, Number 1
Patients with central nervous system infection
Language: Spanish
References: 29
Page: 11-23
PDF size: 162.14 Kb.
ABSTRACT
Introduction: central nervous system infections are a major health problem. The sudden onset of symptoms, the fatal outcome within a few hours or the remaining sequels makes these diseases have a major social impact.Objective: characterize the central nervous system infections, their behavior and relationship to mortality at “Dr. Carlos J. Finlay” Hospital from January 2009 to December 2013.
Methods: an observational descriptive transversal study was carried out with 100 patients at “Dr. Carlos J. Finlay” Hospital from January 2009 to December 2013. Information was collected through medical records with diagnosis any type of sepsis central nervous system at discharge and from autopsy reports. Univariate and Bivariate statistical analyzes were conducted, and the distributions of absolute and relative frequencies were found.
Results: the average age was 44.4 years, there was male predominance in the group ≤ 39 years (54.7 %), but 40-59 years (34.9 %) prevailed in the female group. the deceased group, 60-79 years (47.8 %) majored and those living at discharge, the predominance was ≤ 39 years (53.2 %).Risk factors occurred in the 64 % of patients. Bacterial and viral meningencephalitis accounted for the 77 %. Citochemical testing was performed in 98 % of the patients and it proved positive in the 88, 8 %. The most frequent ethiological agent was Streptococcus pneumoniae (33, 3 %). Complications were present in 33, 7 % of the patients. The rate mortality reached 23 %.
Conclusions: mortality due to CNS infection was high and the isolation of microorganisms was low. The fact that more than a third of patients have complicated substantiates the high mortality in the study.
REFERENCES
Ropper AH, Samuels MA. Infections of the Nervous System (Bacterial, Fungal, Spirochetal, Parasitic) and Sarcoidosis. In: Ropper AH, Samuels MA. Adams and Victor’s Neurology [Internet]. New York: McGraw-Hill; 2012 [cited 2013 Jun 17]. Available from: http://www.accessmedicine.com/content.asp?xaID=3635254
Roos KL, Tyler KL. Meningitis, Encephalitis, Brain Abscess, and Empyema. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J. Harrison's Principles of Internal Medicine [Internet]. 18th ed. New York: McGraw-Hill; 2012. Chapter 381. [cited 2013 Jun 17]. Available from: http://www.accessmedicine.com/content.aspx?aID=9148002
Jiménez Martínez MC, Padilla Docal B. Caracterización de la meningoencefalitis en el Hospital Militar Central "Dr. Luis Díaz Soto", 2004-2008. Rev Cubana Hig Epidemiol [Internet]. 2012 Ago [citado 31 Mar 2013];50(2):[aprox. 8 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561- 30032012000200007&lng=es&nrm=iso&tlng=es
Iparraguirre Góngora O, Álvarez Pena MA, Alba Pérez M, Piriz Assa AR. Relación glucorraquia/glucemia y certeza del diagnóstico de meningoencefalitis viral y bacteriana en urgencias. Rev Cubana Med Int Emerg [Internet]. 2009 [citado 31 Mar 2013];8(2):1495-504. Disponible en: http://bvs.sld.cu/revistas/mie/vol8_2_09/mie04209.htm
López Torres O, Montalván González G, Martínez López JA, Varela Terciado O, Berdayes Milián JD, Reina Álvarez D, et al. Aplicación retrospectiva del score para meningoencefalitis bacteriana en pacientes ingresados con síndrome neurológico infeccioso durante 5 años. Hospital Provincial Pediátrico Docente. Matanzas. 2001, 2003-2006. Rev Méd Electrón [Internet]. 2011 [citado 12 Dic 2012];33(3):293- 301. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1684- 18242011000300006&lng=es
Madrid JA, Pacheco-Hernández P, Jiménez-Islas VG, Hernández CA, Sánchez- Reyes BA, Ortiz MI. Brain empyema due to Escherichia coli in a 5 month-old infant: a case report and literature review. Medwave [Internet]. 2012 Nov [citado 10 Ene 2013];12(10):[aprox. de 6 p.]. Disponible en: www.mednet.cl/link,cgi/Medware/EstuCasosdios//5555
Chen SF, Lu CH, Lui CC, Huang CR, Chuang YC, Tan TY, et al. Acute/subacute cerebral infarction (ASCI) in HIV-negative adults with cryptococcal meningoencephalitis (CM): a MRI-based follow-up study and a clinical comparison to HIV-negative CM adults without ASCI adults without ASCI. BMC Neurol [revista en Internet]. 2011 Jan 26 [citado 27 Abr 2012];11(12):[aprox. 21 p.]. Disponible en: http://www.biomedcentral.com/1471-2377/11/12