2015, Number 2
<< Back Next >>
An Med Asoc Med Hosp ABC 2015; 60 (2)
Childhood cancer in a medically uninsured program in Mexico. Epidemiologic considerations
Rivera-Luna R, Cárdenas-Cardos R, Olaya-Vargas A, Shalkow-Klincovstein J, Pérez-García M, Pérez-González OA, Díaz-Jiménez V, Amador-Zarco JJ, Melchor VY
Language: Spanish
References: 32
Page: 91-97
PDF size: 238.61 Kb.
ABSTRACT
Background: This study comprises those children with cancer registered in the National Council for the Prevention and Treatment of Childhood and Adolescent Cancer. This National Council offers a free comprehensive medical coverage in 55 accredited institutions by the National Center for diseases of children and adolescents. Only children without any government medical insurance qualify for this program. All patients were treated with the same protocols for each of their diseases nationwide.
Methods: The data analyzed were from 2007 to 2012 in children with the pathology diagnosis of cancer from 0 to 18 years old. The parameters studied included age, gender, site of registration-hospital, prevalence, incidence, overall survival, mortality and rate of abandonment.
Results: A total of 14,178 children with newly diagnosed cancer were studied, the mean age was 4.9 years. Males predominated in 55.5%. The incidence rate in 2012 was 156.9/million/year. The most common was leukemia with a prevalence of 49.8% and an incidence of 78.1/million/year (2012). The overall survival was of 68% nation leukemia with a prevalence of 49.8% and an incidence of 78.1/million/year (2012). The overall survival was of 68% nation wide. The mortality rate was 5.3/100,000 in 2012. However a higher proportion was observed among the group from 15 to 18 years with a rate of 8.6. Only 4.7% of these children abandon treatment and/or follow-up.
Conclusion: A high incidence rate of childhood cancer is documented in Mexican children. This program demonstrates that these children have a reasonable good prognosis nationwide. These results are one of the best in Latin America. This program demonstrates an acceptable treatment results with relatively low morbidity and mortality.
REFERENCES
Gupta S, Rivera R, Ribeiro RC, Howard SC. Pediatric oncology as the next global child health priority: the need for national childhood cancer strategies in low and middle-income countries. PLoS Med. 2014; 11 (6): e1001656.
Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015; 136 (5): E359-386.
Diario Oficial de la Federación: Decreto de creación del Consejo Nacional para la Prevención y el Tratamiento del Cáncer en la Infancia y Adolescencia. México; 79-81. Miércoles 5 de enero de 2005.
Steliarova–Foucher E, Stiller C, Lacour B, Kaatsch P. International classification of childhood cancer, third edition. Cancer. 2005; 103: 1457-1467.
Rivera R, Correa G, Altamirano A, Sánchez Z, Cárdenas C, Escamilla A et al. Incidence of childhood cancer among Mexican children registered under a public medical insurance program. Int J Cancer. 2013; 132 (7): 1646-1650.
Censo Poblacional de la República Mexicana: 2010. [Consultada 15 de junio de 2014] Disponible en: http://www.inegi.org.mx.
Perfil epidemiológico del cáncer en niños y adolescentes en México. [Consultada 11 de febrero de 2014] Disponible en: http://www.epidemiologia.salud.gob.mx/doctos/infoepid/publicaciones/2011/monografias/P_EPI_DEL_CANCER_EN_NI%C3%91OSyADOLESCENTES_MEXICO.pdf.
Rivera R. Conceptos epidemiológicos del cáncer infantil en México. En: Rivera-Luna R. Hemato-oncología pediátrica. Principios generales. México: Ed. Editores de Textos Mexicanos; 2006. pp. 1-16.
Ribeiro RC. Improving survival of children with cancer worldwide: the St. Jude international outreach program approach. Stud Health Technol Inform. 2012; 172: 9-13.
Magrath I, Steliarova E, Epelman S, Ribeiro RC, Harif M, Li CK et al. Paediatric cancer in low-income and middle-income countries. Lancet Oncol. 2013; 14: e104-e116.
Farmer P, Frenk FM, Knaul FM, Shulman LN, Alleyne G, Armstrong L et al. Expansion of cancer care and control in countries of low and middle income: a call to action. Lancet. 2010; 376: 1186-1193.
Howlader N, Noone AM, Krapcho M, Neyman N, Aminou R, Waldron W et al. SEER cancer statistics review, 1975-2008, National Cancer Institute. Bethesda, MD. [Consultada 08 de junio de 2014] Disponible en: http://seer.cancer.gov/csr/1975_2008/.
Petridou ET, Sergentanis TN, Panagopoulou P, Moschovi M, Polychronopoulou S, Baka M et al. In vitro fertilization and risk of childhood leukemia in Greece and Sweden. Pediatric Blood Cancer. 2012; 58: 930-936.
Valcke M, Chaverri F, Monge P, Bravo V, Mergler D, Partanen T et al. Pesticide priorization for a case-control study on childhood leukemia in Costa Rica: a simple stepwise approach. Environ Res. 2005; 97: 335-347.
Chang JS. Parenteral smoking and childhood leukemia. Methods Mol Biol. 2009; 472: 103-137.
Perera F. Molecular epidemiology, prenatal exposure and prevention of cancer. Environ Health [Internet]. 2011 [Consultada 22 de octubre de 2014]; 10 (Suppl 1): S1-S3. Disponible en: http://www.ehjournal.net/content/10S1/S5.
Greaves M. Infection, immune responses and the aetiology of childhood leukaemia. Nat Rev Cancer. 2006; 6: 193-203.
Kellie SJ, Howard SC. Global child health priorities: what role for paediatric oncologists? Eur J Cancer. 2008; 44: 2388-2396.
Pan IJ, Daniels JL, Zhu K. Poverty and childhood cancer incidence in the United States. Cancer Causes Control. 2010; 21: 1139-1145.
Ribeiro RC, Sterialova-Foucher E, Magrath I, Lemerle J, Eden T, Forget C et al. Baseline status of paediatric oncology care in ten low-income or mid-income countries receiving my child matters support: a descriptive study. Lancet Oncol. 2008; 9: 721-729.
Howard SC, Ortiz R, Baez LF, Cabanas R, Barrantes J, Fu L et al. Protocol-based treatment for children with cancer in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-part II. Pediatr Blood Cancer. 2007; 48: 486-490.
Curado MP, Pontes T, Guerra-Yi ME, Cancela MC. Leukemia mortality trends among children, adolescents, and young adults in Latin America. Rev Panam Salud Pública. 2011; 29: 96-102.
Chatenoud L, Bertuccio P, Bosetti C, Levi F, Negri E, La Vecchia C. Childhood cancer mortality in America, Asia, and Oceania, 1970 through 2007. Cancer. 2010; 116: 5063-5074.
Sullivan R, Kowalczyk JR, Agarwal B, Ladenstein R, Fitzgerald E, Barr R et al. Improving cancer care for children and young people 4. New policies to address the global burden of childhood cancers. Lancet Oncol. 2013; 14: e125-e135.
Hsu SC, Metzger ML, Hudson MM, Pedrosa F, Lins M, Pedrosa M et al. Comparison of treatment outcomes of childhood Hodgkin lymphoma in two US centers and a center in Recife, Brazil. Pediatr Blood Cancer. 2007; 49: 139-144.
Goldsby RE, Taggart DR, Ablin AR. Surviving childhood cancer: the impact on life. Paediatr Drugs. 2006; 8: 71-84.
Dantés OG, Sesma S, Becerril VM, Knaul FM, Arreola H, Frenk J. The health system of Mexico. Salud Pública Mex. 2011; 53 (Suppl 2): s220–s232.
Calaminus G, Birch JR, Hollis R, Pau B, Kruger M. The role of SIOP as a plataform for communication in the global response to childhood cancer. Pediatr Blood Cancer. 2013; 60: 2080-2086.
Howard SC, Marinoni M, Castillo L, Bonilla M, Tognoni G, Luna-Fineman S et al. Improving outcomes for children with cancer in low-income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO)-Part 1. Pediatr Blood Cancer. 2007; 48: 364-369.
Pérez-Cuevas R, Duobova SV, Zapata-Tarres M, Flores-Hernández S, Frazier L, Rodríguez-Galindo C et al. Scaling up cancer care without medical insurance in developing countries: the case of Mexico. Pediatr Blood Cancer. 2013; 60: 196-203.
Rivera-Luna R, Correa-González C, Altamirano-Alvarez E, Sánchez-Zubieta F, Cárdenas-Cardós R, Escamilla-Asian G et al. Incidence of childhood cancer among Mexican children registered under a public medical insurance program. Int J Cancer. 2013; 132: 1646-1650.
Rivera-Luna R, Shalkow-Klincovstein J, Velasco-Hidalgo L, Cardenas-Cardos R, Zapata-Tarres M, Olaya-Vargas A et al. Descriptive epidemiology in Mexican children with cancer under an open national public health insurance program. BMC Cancer. 2014; 14: 790-798.