2013, Number 6
Alcohol, liver and genes: an intricate puzzle
Rosso N, Tiribelli C
Language: English
References: 0
Page: 860
PDF size: 53.43 Kb.
Text Extraction
Genetic factors affecting susceptibility to alcoholic liver disease in an Indian populationKumar DA. Alcoholic liver disease (ALD) results from a complex interaction between behavioral, environmental, and genetic factors. Although several studies have defined a close relationship between cumulative alcohol intake and risk of developing liver damage, extensive individual variability exists in disease susceptibility. Even among heavy drinkers (more that 100 g alcohol per day), only some individuals develop clinical, biochemical, and histological signs of ALD, ranging from 5-40% in the different series.