2013, Número 6
Treatment of chronic hepatitis C virus infection in the near future
Idioma: Ingles.
Referencias bibliográficas: 33
Paginas: 854-859
Archivo PDF: 90.98 Kb.
FRAGMENTO
Sin resumen.REFERENCIAS (EN ESTE ARTÍCULO)
A SPECIAL MEETING REVIEW EDITION: Advances in the Treatment of Hepatitis C Virus Infection From EASL 2013: The 48th Annual Meeting of the European Association for the Study of the LiverApril 24-28, 2013 • Amsterdam, The NetherlandsSpecial Reporting on:• Simeprevir Plus Peginterferon/ Ribavirin Is Associated with a High SVR12 Rate in Treatment-Naive Patients with Genotype 1 Hepatitis C Virus Infection• Addition of Simeprevir to Peginterferon/Ribavirin Is Associated with Faster Resolution of Fatigue in Treatment-Naive Patients• Sofosbuvir Plus Ribavirin Demonstrates Significant Efficacy in Multiple HCV Genotype 2/3 Populations• Daclatasvir Plus Sofosbuvir with or without Ribavirin Yields 100% SVR24 Rate in Genotype 1 Patients Who Fail Telaprevir or Boceprevir• Addition of TG4040 Vaccine to Peginterferon/Ribavirin Increases Sustained Virologic Response Rate at 24 Weeks in Genotype 1 Hepatitis C InfectionPLUS Meeting Abstract Summaries With Expert Commentary by: Ira M. Jacobson, MDJoan Sanford I. Weill Medical College at Cornell UniversityNew York, New York. Gastroenterol Hepatol (NY) 2013; 9(Suppl. 3): 1-18.
Jacobson I, Dore GJ, Foster GR, et al. Simeprevir (TMC435) with peginterferon/ribavirin for chronic HCV genotype 1 infection in treatment-naïve patients: results from QUEST-1, a phase III trial. Presented at the 48th Annual Meeting of the European Association for the Study of the Liver; April 24–28, 2013; Amsterdam, the Netherlands. Abstract 1525.
Manns M, Marcellin P, Poordad FP, et al. Simeprevir (TMC435) with peginterferon/ribavirin for treatment of chronic HCV genotype-1 infection in treatment- naive patients: results from QUEST-2, a phase III trial. Presented at the 48th Annual Meeting of the European Association for the Study of the Liver; April 24–28, 2013; Amsterdam, the Netherlands. Abstract 1413.
Zeuzem S, Berg T, Gane E, et al. TMC435 in HCV genotype 1 patients who have failed previous pegylated interferon/ ribavirin treatment: final SVR24 results of the ASPIRE trial. Presented at the 47th Annual Meeting of the European Association for the Study of the Liver; April 18–22, 2012; Barcelona, Spain. Abstract 2.
Lawitz E, Ghalib R, Rodriguez-Torres M, et al. Suppression of Viral Load through 4 Weeks Post-Treatment Results of a Once-daily Regimen of Simeprevir + Sofosbuvir with or without Ribavirin in Hepatitis C Virus GT 1 Null Responders. 20th Conference on Retroviruses and Opportunistic Infections. Atlanta, March 3-6, 2013. Abstract 155LB.
Ferenci P, Asselah T, Foster GR, et al. Falaprevir plus pegylated interferon alfa2a and ribavirin in chronic HCV genotype- 1 treatment-naïve patients: Final results from STARTVERSO1, a randomized, placebo-controlled phase III trial. 48th Annual Meeting of the European Association for the Study of the Liver, April 24-28, 2013, Amsterdam, Netherlands; abstract 1416.
Kowdley KV, Lawitz E, Poordad F, et al. A 12-week interferon- free treatment regimen with ABT-450/r, ABT-267, ABT-333 and ribavirin achieves SVR rates (observed data) of 99% in treatment-naïve patients and 93% in prior null responders with HCV genotype 1 infection. 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2012). Boston, November 9-13, 2012. Abstract LB-1.
Dore GJ, Lawitz E, Hezode C, et al. Daclatasvir combined with peginterferon alfa 2a alfa-and ribavirin for 12 or 16 weeks in patients with hepatitis c virus genotype 2 or 3 infection: command gt 2/3 study. Presented at the 48th Annual Meeting of the European Association for the Study of the Liver; April 24–28, 2013; Amsterdam, the Netherlands. Abstract 1418.
Everson GT, Sims KD, Rodriguez-Torres M, et al. Interim analysis of an interferon (IFN)- and ribavirin (RBV)-free regimen of daclatasvir (DCV), asunaprevir (ASV), and BMS- 791325 in treatment-naive, hepatitis C virus genotype 1- infected patients. Presented at the 48th Annual Meeting of the European Association for the Study of the Liver; April 24–28, 2013; Amsterdam, the Netherlands. Abstract 1417.
Sulkowski MS, Gardiner DF, Rodriguez-Torres M, et al. High rate of sustained virologic response with the all-oral combination of daclatasvir (NS5A inhibitor) plus sofosbuvir (nucleotide NS5B inhibitor), with or without ribavirin, in treatment-naïve patients chronically infected with HCG GT 1, 2, or 3. Presented at the 63rd Annual Meeting of the American Association for the Study of Liver Diseases; November 9–13, 2012; Boston, Massachusetts. Abstract LB-2.
Sulkowski MS, Gardiner DF, Rodriguez-Torres M, et al. Sustained virologic response with daclatasvir plus sofosbuvir plus/minus ribavirin (RBV) in chronic HCV genotype (GT) 1- infected patients who previously failed telaprevir (TVR) or boceprevir (BOC). Presented at the 48th Annual Meeting of the European Association for the Study of the Liver; April 24–28, 2013; Amsterdam, the Netherlands. Abstract 1417.