medigraphic.com
Colegio de Medicina Interna de México.

2015, Number 3

<< Back Next >>

Med Int Mex 2015; 31 (3)

Risk factors of death due to influenza-like illness in Mexican hospitals

Rodríguez-Moctezuma JR, Bautista-Velázquez A, Pineda-Carranza A, Chacón-Sánchez J, Jiménez-Luna J, López-Ocaña LR

Language: Spanish
References: 15
Page: 281-288
PDF size: 289.62 Kb.


ABSTRACT

Background: There are factors associated with poor prognosis and death in patients with influenza-like illness (ILI) that the physician should know to take the necessary measures in the care of patients.
Objective: To determine risk factors associated with mortality in patients admitted to IMSS hospitals in the State of Mexico during the influenza contingency.
Material and method: A case-control study in which records of 53 patients who died of pneumonia were reviewed and matched for hospital survivors with the same diagnosis. Data at entering and clinical development information were collected.
Results: It was established that there was no difference in mortality when any antibiotics, steroids or bronchodilators were administered. Prescription antiviral at entering of patients is associated with lower mortality, p‹ 0.05. More time before admission and the presence of multiple pulmonary infiltrates were associated with increased mortality, p‹ 0.005. Other risk factors associated with death were the use of mechanical ventilation with RM 46.6 (95% CI 8.41-258.0) and pneumonia with multiple bindings, RM 5.38 (95% CI 1.28-22.50).
Conclusions: Risk factors associated with death in patients with influenza-like illness were: not administration of antiviral treatment at entering, male sex, multiple pulmonary infiltrates or any chronic disease.


REFERENCES

  1. Centers for Disease Control and Prevention (CDC). Update: Infections with a swine-origin influenza A (H1N1) virus-United States and other countries. MMWR Morb Mortal Wkly Rep 2009;58:431-433.

  2. Novel swine-origin influenza A (H1N1) Virus Investigation Team, Dawood FS, Jain S, Finelli L, Shaw MW, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Eng J Med 2009;360:2605-2615.

  3. López-Cervantes M, Venado A, Moreno A, Pacheco-Dominguez RL, Ortega-Pierres G. On the spread of the novel influenza A (H1N1) virus in México. J Infect Dev Ctries 2009;3:327-330.

  4. Brote de Influenza Humana A H1N1. Dirección General Adjunta de Epidemiología, 2009. Disponible en : http://portal.salud.gob.mx/contenidos/noticias/influenza/estadisticas/.html.

  5. Echeverría-Zuno S, Mejía-Aranguré JM, Mar-Obeso AJ, Grajales-Muñiz C, et al. Infection and death from influenza A H1N1 virus in Mexico a retrospective analysis. Lancet 2009;374:2072-2079.

  6. Perez-Padilla R, De la Rosa Zamboni D, Ponce de León S, Hernández M, et al. Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. N Engl J Med 2009;361:680-689.

  7. Writing committee of the WHO consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza, Bautista E, Chotpitayasunondh T, Gao Z, Harper SA, et al. Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med 2010;362:1708-1719.

  8. Capelastegui A, España PP, Quintana JM, Gorordo I y col. Pacientes ingresados por neumonía adquirida en la comunidad: Estudio comparativo en función de la especialidad del servicio médico responsable. Arch Bronconeumol 2005;41:300-306.

  9. Del Bufalo C, Morelli A, Bassein L, Fasano L, et al. Severity scores in respiratory intensive care: APACHE II predicted mortality better than SAPS II. Respir Care 1995,40:1042-1047.

  10. Jain S, Benoit SR, Skarbinski J, Bramley AM, Finelli L. Influenza-associated pneumonia among hospitalized patients with 2009 pandemic influenza A (H1N1) virus-United States 2009. Clin Infect Dis 2012;54:1221-1229.

  11. Wilking H, Buda S, von der Lippe E, Altmann D, et al. Mortality of 2009 pandemic influenza A (H1N1) in Germany. Euro Surveill 2010;15:1-6.

  12. Bewick T, Myles P, Greenwood S, Nguyen-Van-Tam JS, et al. Clinical and laboratory features distinguishing pandemic H1N1 influenza-related pneumonia from interpandemic community-acquired pneumonia in adults. Thorax 2011;66:247-252.

  13. Orizaga-Franco T, Rosas-Moreno M de JR, Morales-Blanhir JE. El cuadro clínico y laboratorio. Neumología y Cirugía de Tórax 2007;66:23-28.

  14. Harper SA, Bradley JS, Englund JA, File TM, et al. Seasonal influenza in adults and children-diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: of America. IDSA Guidelines. Clin Infect Dis 2009:48:103-132.

  15. Luna CM, Monteverde A, Rodríguez A, Apezteguia C y col. Neumonía intrahospitalaria: guía clínica aplicable a Latinoamérica preparada en común por diferentes especialistas. Arch Bronconeumol 2005;41:439-456.




2020     |     www.medigraphic.com