2015, Number 2
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Rev Mex Patol Clin Med Lab 2015; 62 (2)
C-reactive protein: a potential marker for bacterial pneumonia in children
Hortal M, Estevan-Collazo M, Meny M
Language: Spanish
References: 11
Page: 97-99
PDF size: 201.60 Kb.
ABSTRACT
Introduction: Streptococcus pneumoniae etiology is poorly defined in children’s pneumonia. To overcome this problem, the World Health Organization recommended standardized chest radiograph interpretation as an epidemiological marker to provide a reasonable approach to bacterial pneumonia (presumed pneumococcal). Pneumococcal conjugate vaccine application reduced the incidence of consolidated pneumonias in hospitalized children, but a reduction was also recorded among non-consolidated pneumonias. Therefore, C-reactive protein (CRP) was proposed as an additional marker.
Objective: To assess the frequency of CRP ≥ 40 mg/L associated with pneumonias among hospitalized children.
Methods: Retrospective data abstracted from clinical reports provided C-reactive protein results and chest x-ray classifications. Significant cut off for CRP serum concentration was ≥ 40 mg/L.
Results: Among patients with consolidated pneumonia, CRP high values predominated, but significant values were also associated with non-consolidated pneumonias. Pneumococcal pneumonias and pleural effusions showed high CRP levels.
Conclusion: The recorded CRP results associated with chest X-ray interpretations point to a potential participation of S. pneumoniae in pediatric pneumonias. A prospective study is needed to further explore the potential contribution of both markers for bacterial pneumonia estimation.
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