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2001, Number 1

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Rev Mex Patol Clin Med Lab 2001; 48 (1)

Helicobacter pylori prevalence in Children at School Age

Lagunes YB, Calva RR, Ramírez TE

Language: Spanish
References: 30
Page: 23-26
PDF size: 74.52 Kb.


ABSTRACT

Introduction: Helicobacter pylori produces chronic inflammation in gastric mucosa and causes several types of gastritis, going from chronic and superficial gastritis to atrophic one, and to gastric adenocarcinoma. There are certain studies showing a changing infection percentage occurring on children, depending on age and socio-economic conditions. The aim of this study was to know, in a sample of apparently healthy children from a middle-low class population, active infection prevalence and its correlation to symptomatology and diverse risk factors implied in it. Materials and Methods: Two groups of children coming from two different schools and ranging from 6 to 13 years old, with a 9-year average, 46 males (49%) and 48 females (51%) were studied. After parents and administrators consent, they were applied a survey in order to assess risk factors and symtomatology in 94 children chosen at random. They were required a feces sample to determinate Helicobacter pylori antigen presence. Ji quadratic and Fisher Exact statistical tests were employed. Results: There were 23 positive results for Helicobacter pylori antigen (24.5%) and 71 (75%) were negative. There were 13 samples from male children showing positive results (14%), as well as 10 (10.5%) from female children, without showing any statistical significance about gender, according to Fisher Exact test. In regard to the studied risk factors, such as weekly frequency in meat ingestion, breakfast habits, stacking, potable water, cohabiting with wild or domestic animals, and symptom histories, such as stomachaches and frequent diarrhea periods, there was no significance, with values of p‹0.734, employing Ji quadratic.


REFERENCES

  1. Marshall BJ, Warren JR. Unidentified curved bacilli in gastric epithelium in active chronic gastritis. Lancet 1993; 1: 1273-1275.

  2. Dooley CP, Cohen H. The clinical significance of Campylobacter pylori. Ann Inter Med 1988; 108: 70-79.

  3. Sipponen P. Helicobacter pylori gastritis epidemiology. J Gastroenterol 1997; 32: 273-277.

  4. López-Corella E. Helicobacter pylori en pediatría. Patología 1997; 35: 110-112.

  5. Neale KR, Logan RP. The epidemiology and transmission of Helicobacter pylori infection in children. Aliment Pharmacol Ther 1995; 9: 77-84.

  6. Rowland M, Drumm B. Clinical significance of Helicobacter infection in children. Br Med Bull 1998; 54: 95-103.

  7. Makristathis A, Pasching E, Schutze, Wimmer M, Rotter ML, Hirschl AM. Detection of Helicobacter pylori in Stool Specimens by PCR and Antigen Enzyme Immunoassay. J Clin Microbiol 1998; 36: 2772-2774.

  8. Rothenbacher D, Bode G, Berg G, Gommel R, Gonser T, Adier G, Brenner H. Prevalence and determinants of Helicobacter pylori infection in preschool children: a population based study from Germany. Int J Epidemiol 1998; 27: 135-141.

  9. Bode G, Rothenbacher D, Brenner H, Adler G. Pets are not risk factor for Helicobacter pylori infection in young children: results of a population based study in Southern Germany. Pediatr Infect Dis J 1998; 17: 909-912.

  10. Bode G, Rothenbacher D, Brenner H, Adier G. Helicobacter pylori and abdominal symptoms: A population based study among preschool children in Southern Germany. Pediatrics 1998; 101: 634-637.

  11. Hardikar W, Grimwood K. Prevalence of Helicobacter pylori infection in asymptomatic children. J Paediatr Child Health 1995; 31: 537-541.

  12. Czkwianianc E, Bak Romaniszyn L, Melecka Panas E, Suski S, Woch G. Prevalence of Helicobacter pylori in children dependently on age and living conditions. J Physiol Pharmacol 1996; 47: 203-207.

  13. Oliveira AM, Queiroz DM, Rocha GA, Mendes EN. Sero-prevalence of Helicobacter pylori infection in children of low socioeconomic level in Belo Horizonte Brazil. Am J Gastroenterol 1994; 89: 2201-2204.

  14. Webb PM, Knight T, Greaves S, Wilson A, Neweil DG, Elder J, Forman D. Relation between infection with Helicobacter pylori and living conditions in chlidhood: evidence for person to person transmission in early life. Br Med J 1994; 19: 750-753.

  15. Ozturk H, Senocak ME, Uzunalimoglu B, Hascelik G, Buyukpamukcu N, Hicsonmez A. Helicobacter pylori infection in symptomatic and asymptomatic children: a prospective clinical study. Eur J Pediatr Surg 1996; 6: 265-269.

  16. Fraser AG, Seragg R, Metcalf P, McCullougb S, Yeates NJ. Prevalence of Helicobacter pylori infection in different ethnic groups in New Zeland children and adults. Aust NZJ Med 1996; 26: 646-651.

  17. Clemens J, Albert MJ, Rao M, Huda S, Qadri F, Van Loon FP, Pradhan B, Naficy A, Banik A. Sociodemographic, hygienic and nutritional correlates of Helicobacter pylori infection of young Bangladeshi children. Pediatric Infect Dis 1996; 15: 1113-1118.

  18. Malaty HM, Paykov V, Bykova O, Ross A, Graham DP, Anneger JF, Graham DY. Helicobacter pylori and socioeconomic factors in Russia. Helicobacter 1996; 2: 82-87.

  19. Elitsur Y, Short JP, Neace C. Prevalence of Helicobacter pylori infection in children from urban and rural West Virginia. Dig Dis Sci 1998; 43: 773-778.

  20. Cilla G, Perez-Trallero E, Garcia-Bengoechea M, Marimon JM, Arenas JI. Helicobacter pylori infection: a seroepidemiological study in Guipuzcoa, Basque Country, Spain. Eur J Epidemiol 1997; 13: 945-949.

  21. Torres J, Leal-Herrera Y, Perez-Perez G, Gomez A, Camorlinga-Ponce M, Cedillo-Rivera R, Tapia-Coyner R, Muñoz O. A community-based seroepidemiologic study of Helicobacter pylori infection in Mexico. J Infect Dis 1998; 178: 1089-1094.

  22. Lindkvist P, Enquselassle F, Asrat D, Muhe L, Nilsson I, Glesecke J. Risk factors for infection with Helicobacter pylori a study of children in rural Ethiopia. Scand J Infect Dis 1998; 30: 371-376.

  23. Sathar MA, Gouws E, Simjee AE, Mayat AM. Seroepidemiological study of Helicobacter pylori infection in South African children. Trans R Soc Trop Med Hyg 1997; 91: 393-395.

  24. Kurilovich SA, Reshetnikov OV, Granberg C, Haiva VM, Danliov AS, Babin VP. Epidemiology of Helicobacter pylori infection in various regions of Siberia and Far East. Gut 1997: 41-39A.

  25. Pilott A, Fabrello R, Franceschi M, Scagnelli M, Soffiati F, Di Mario F, Fortunato A, Valerio G. Helicobacter pylori infection in asymptomatic elderly subjects living at home or in a nursing home: effects on gastric function and nutritional status. Age Ageing 1996; 25: 245-249.

  26. Mahalanabis D, Rahman MM, Sarker SA, Bardhan PK, Hildebrand P, Beglinger C, Gyr K. Helicobacter pylori infection in the young in Bangladesh: prevalence, socioeconomic and nutritional aspects. Int J Epidemiol 1996; 25: 894-898.

  27. Kehrt R, Becker M, Brosicke H, Kruger N, Helge H. Prevalence of Helicobacter pylori infection in Nicaraguan children with persistent diarrhea, diagnosed by 13C-urea breath test. J Pediatr Gastroenterol Nutr 1997; 25: 84-88.

  28. Klein PD, Graham DY, Gaillour A, Opekun AR, Smith EO. Water source as risk factor for Helicobacter pylori infection in Peruvian children. Lancet 1991; 337: 1503-1506.

  29. Ansorg R, Von Heinegg EH, Von Reckinghausen G. Cat owners’ risk of acquiring a Helicobacter pylori infection. Zentralbl Bakteriol 1995; 283: 122-126.

  30. Fiedorek SC, Malaty HM, Evans DL, Pumphrey CL, Casteel HB, Evans DJ, Graham DY. Factors influencing the epidemiology of Helicobacter pylori infection in children. Pediatrics 1991; 88: 578-582.




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