2015, Number 1
<< Back Next >>
Revista Cubana de Angiología y Cirugía Vascular 2015; 16 (1)
Infantile haemangioma
de la Cruz FY
Language: Spanish
References: 49
Page: 76-91
PDF size: 147.34 Kb.
ABSTRACT
Introduction: infantile hemangioma is one of the main reasons for pediatric
consultation. The nomenclature used to define this type of lesion has constantly
undergone changes throughout history, which has resulted in some confusion. It is
essential to have knowledge on the current classification of the different vascular
lesions that may have similar clinical characteristics but different progression,
prognosis and treatment.
Objective: to delve into and broaden knowledge on the current diagnosis and
treatment of infantile hemangioma.
Methods: a literature review was made to locate articles in the most important online
databases, including Medline, Cochrane Library, Lilacs, and the meta-searcher
Google. The years of publications comprised 2009 through 2014.
Data synthesis: infantile hemangiomas are the most frequent benign tumors in
breastfed children. They account for 1.1 to 2.6 %. They are more common in
Caucasians, in females (3:1 or 5:1). They occur occasionally and t can be found in
any anatomical region, mainly in the head and the neck. Their diagnosis is clinical,
most of them are small and do not require treatment.
Conclusions: it is necessary to spread the knowledge on infantile hemangioma as we
are the first ones to receive these patients, so timely diagnosis is vital to start an
early treatment if required.
REFERENCES
de Lucas Laguna R. Angiomas y malformaciones vasculares, ¿qué debo saber? En: AEPap, editor. Curso de actualización pediatría 2013. Madrid: Exlibris Ediciones; 2013. p. 49-56.
Mulliken JB, Glowacki J. Hemangiomas and vascular malformations in infants and children: a classification based on endothelial characteristics. Plast Reconstr Surg. 1982;69:412-22.
Lobos HC. Hemangiomas de la infancia. Manejo actual. Rev Med Clin Condes. 2011;22(6)825-33.
Schwalb G, Cocca A, Attie M, Basack N, Aversa L. Malformaciones vasculares en pediatría. Hematología. 2013;17(1):55-9.
Baselga E. hemangiomas infantiles. TheaInformación. 2012;(26):5-29.
Enjolras O, Mulliken JB. Vascular tumors and vascular malformations (new issues). Adv Dermatol. 1997;13:375-423.
Garzon MC, Huang JT, Enjolras O, Frieden IJ. Vascular malformations: Part I. J Am Acad Dermatol. 2007;56:353-70.
Pérez L. Lesiones vasculares de la infancia y síndromes asociados. En: Herane MI, Urbina F, editores. Dermatología III Pediátrica. 2da ed. Chile; Salecianos Impresores; 2010. p. 41-8.
Schwartz RA, Sidor MI, Musumeci ML, Lin RL, Micali G. Infantile haemangiomas: a challenge in Paediatric Dermatology. J Eur Acad Dermatol Venereol. 2010;24:631-8.
Bruckner AL, Frieden IJ. Hemangiomas of infancy. J Am Acad Dermatol. 2003;48:477-93.
North PE, Milton Waner M, Mizerack A, Mrak RE, Nicholas R, Kincannon J, Suen JY, Mihm MC, et al. A unique microvascular phenotype shared by juvenile hemangiomas and human placenta. Arch Dermatol. 2001:137(5):559-70.
Trindade F, Tellechea O, Torrelo A, Requena L, Colmenero I. Wilms tumor 1 expression in vascular neoplasms and vascular malformations. Am J Dermatopathol. 2011;33:569-72.
Frieden IJ, Haggstrom AN, Drolet BA, Mancini AJ, Friedlander SF, Boon L, et al. Infantile hemangiomas: Current knowledge, future directions. Proceedings of a research workshop on infantile hemangiomas. Pediatr Dermatol. 2005;22:383-406.
Burton BK, Schulz CJ, Angle B, Burd LI. An increased incidence of haemangiomas in infants born following chorionic villus sampling (CVS). Prenat Diagn. 1995;15:209-14.
González-Díaz MP, Ramos-Gómez LI, Yañez-Sánchez JM, Marines-Sánchez HM, Páez-Garza JH. Uso sistémico de propanolol en el tratamiento de hemangiomas infantiles. Rev Mex Oftalmol. 2011;85(4):205-14.
López R, López JC, Belendez C, Herrero A, Mateo ME, Ramírez G. Tumores vasculares en la infancia. An Pediatr (Barc). 2010;72(02):143-5.
Sánchez-Carpintero I, Ruiz-Rodríguez R, López-Gutiérrez JC. Propanolol en hemangiomas infantiles: eficacia clínica, riesgos y recomendaciones. Actas Dermosifiliogr. 2011;102(10):766-79.
Balma-Mena A, Lara-Corrales I. Clasificación, manejo y complicaciones de los hemangiomas de la infancia. Acta Pediátr Costarric. 2012;22(1):7-13.
Waner M, North PE, Scherer KA, Frieden IJ, WanerA, Mihm MC. The nonrandom distribution of facial hemangiomas. Arch Dermatol. 2003;139(7):869-75.
Enjolras O, Gelbert F. Superficial hemangiomas: associations and management. Pediatr Dermatol. 1997;14:173-9.
Shayan YR, Prendiville JS, Goldman RD. Use of propranolol in treating hemangiomas. Canadian Family Physician. 2011;57:302-3.
Torres B. Protocolo de actuación diagnóstica de los angiomas en la infancia. Piel. 2008;23(5):249-57.
Léaute-Labrèze C, Prey S, Ezzedine K. Infantile haemangioma: Part I. Pathophysiology, epidemiology, clinical features, life cycle and associated structural abnormalities. J Eur Acad Dermatol Venereol. 2011;25:1245-53.
Léaute-Labreze C, Prey S, Ezzedine K. Infantile haemangioma: Part II. Risks, complications and treatment. J Eur Acad Dermatol Venereol. 2011;25:1254-60.
Kelly ME, Juern AM, Grossman WJ, Schauer DW, Drolet BA. Immuno-suppressive effects in infants treated with corticosteroids for Infantile Hemangiomas. Arch Dermatol. 2010;146:767-74.
Bennett ML, Fleischer AB, Chamlin SL, Frieden IJ. Oral corticosteroid use is effective for cutaneous hemangiomas: an evidence-based evaluation. Arch Dermatol. 2001;137(9):1208-13.
Bagazgoitia L, Torrelo A, Gutiérrez JC, Hernández-Martín A, Luna P, Gutiérrez M, et al. Propranolol for infantile hemangiomas. Pediatr Dermatol. 2011;28:108-14.
Breur JM, Graaf M, Breugem CC, Pasmans SGMA. Hypoglycemia as a result of propranolol during treatment of infantile hemangioma: A case report. Pediatr Dermatol. 2010;28(1):169-71.
Claerhout I, Buijsrogge M, Delbeke P, Walraedt S, De Schepper S, De Moerloose B, de Groote K, Decock C. The use of propranolol in the treatment of periocular infantile haemangiomas: a review. Br J Ophthalmol. 2011;95(9):1199-02.
Hermans DJ, van BIm, Schultze Kool LJ, Van Kerkhof PCM, Andreas Wijnen MHW, Van dervleuten CJM. Propranolol, a very promising treatment for ulceration in infantile hemangiomas: a study of 20 cases with matched historical controls. J Am Acad. Dermatol. 2011;64(5):833-8.
Leaute-Labreze C, Dumas de la RE, Hubiche T, Boralevi F, Thambo Jb, Taieb A. Propranolol for severe hemangiomas of infancy. N Engl J Med. 2008;358:2649-51.
Mhanna A, Franklin WH, Mancini AJ. Hepatic infantile hemangiomas treated with oral propranolol. A case series. Pediatr Dermatol. 2011;10-1470.
Sans V, de la Roque ED, Berge J, Grenier N, Boralevi F, Mazereeuw- Hautier J, et al. Propranolol for severe infantile hemangiomas: follow-up report. Pediatrics. 2009;124(3):e423-31.
Léauté-Labréze C, Hubiche T, Boralevi F, Dumas de la Roque E, Thambo JB, Taibeb A. Les bétabloquantes: une alternative á la corticothérapie générales dans le traitement des hémangiomes infantiles. Journées Dermatoligique Paris. 2007 Dic: 4-8.
Berdión Sevilla E, Hernández Viel V. El Propranolol revoluciona el tratamiento de los hemangiomas en la infancia. Medisan. 2013 [citado 6 Jun 2014];17(7):2065-7. Disponible en: http://www.scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029301920130007000 18&lng=es&nrm=iso
Fieden IJ, Drolet BA. Propanolol for infantile hemangiomas: Promise, peril, pathogenesis. Pediatric Dermatol. 2009;26:610-4.
Bernabeu-Wittel J, Pereyra-Rodríguez JJ, Mantrana-Bermejo ME, Fernández- Pineda I, de Agustínc JC, Conejo-Mir J. Tratamiento con Propranolol oral para hemangiomas infantiles graves: serie de 28 pacientes. Actas Dermosifiliogr. 2011;102(7):510-6.
Bermúdez Loizaga A. Timolol tópico: nueva terapia en el tratamiento de los hemangiomas infantiles. FH. 2012;35:48-50.
Pope E, Chakkittakandiyil A. Topical timolol gel for infantile hemangiomas: a pilot study. Arch Dermatol. 2010;146(5):564-5.
Ho NTC, Lansang P, Pope E. Topical imiquimod in the treatment of infantile hemangiomas: A retrospective study. JAAD. 2007;56(1):63-8.
Enjolras O, Breviere GM, Roger G, Tovi M, Pellegrino B, Varotti E, et al. Traitement par vincristine des hemangiomes graves du nourrisson. Arch Pediatr. 2004;11(2):99-107.
Jiménez Palacios C, Pérez Herrera C, Lugo MV La escleroterapia en el tratamiento de los hemangiomas de los tejidos blandos de la cavidad bucal en estomatología pediátrica. Acta Odontol Venez. 2000;38(2):4-8.
Eun-Kyung MK, Seedelft M, Drolet BA. Infantile Hemangiomas. Am J Clin Dermatol. 2013;14(2):111-23.
Marler JJ, Mulliken JB. Current management of hemangiomas and vascular malformations. Clin Plast Surg. 2005;32:99-116.
López Almaraz R, López Gutiérrez JC, Belendez Bieler C, Herrero Hernández A, Mateos González ME, Ramírez Villar G. Tumores vasculares en la infancia. An Pediatr (Barc). 2010;72(2):143e1-e15.
Bulliken JB, Enjolras O. Congenital hemangiomas and infantile hemangioma: missing links. J Am Acad Dermatol. 2004;50:875-82.
Berenguer B, González Meli B, Marín Molina C, de Tomás Palacios E. Hemangioma congénito rápidamente involutivo (RICH) que simula una fisura labial mínima. Cir Pediatr. 2010;23:130-3.
Scacchi MF, Luna PC, Boggio P, Abad ME, Pagotto B, Larralde M. Hemangiomas de la infancia con crecimiento mínimo o detenido. Dermatol Argent. 2012;18(4):281-5.
Giachetti A, Sojo MM, García-Mónaco R. Hemangiomas infantiles. Arch Argent Pediatr 2013;111(6):537-45.