2014, Number 1-3
<< Back Next >>
Med Cutan Iber Lat Am 2014; 42 (1-3)
Autologous platelet-rich plasma in difficult to heal wounds. Case report
Rodríguez-Zendejas NJ, Contreras-Ruiz J, Garrido-Espíndola X, Romero-Valdovinos M, Lozano-Platonoff A
Language: Spanish
References: 15
Page: 62-64
PDF size: 291.49 Kb.
ABSTRACT
In spite of new knowledge and the development of novel therapies in the field of wound care, many health practitioners encounter difficult to heal wounds, where even after proper care, wound healing is prolonged or stalled. We present a case of a woman with venous insufficiency and a cutaneous ulcer secondary to a dog bite and a very slow healing rate in whom the use of autologous platelet-rich plasma resulted in full wound closure after six weeks
REFERENCES
Winter GD. Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig. Nature. 1962; 193: 293-294.
European Wound Management Association. Position document: hard-to-heal wounds: a holistic approach. London: MEP Ltd; 2008.
Frykberg RG, Driver VR, Carman D, Lucero B, Borris-Hale C, Fylling C et al. Chronic wounds treated with a physiologically relevant concentration of platelet-rich plasma gel: a prospective case series. Ostomy Wound Manage. 2010; 56: 36-44.
Cervelli V, De Angelis B, Lucarini L, Spallone D, Balzani A, Palla L et al. Tissue regeneration in loss of substance on the lower limbs through use of platelet-rich plasma, stem cells from adipose tissue and hyaluronic acid. Adv Skin Wound Care. 2010; 23: 262-272.
Kawase T, Okuda K, Wolff LF, Yoshie H. Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and ostoblastic cells in vitro. J Periodontol. 2003; 74: 858-864.
Driver VR, Hanft J, Fylling CP, Beriou JM, Autogel Diabetic Foot Ulcer Study Group. A prospective, ramdomized, controlled trial of autologous platelet-rich plasma gel for the treatment of diabetic foot ulcers. Ostomy Wound Manage. 2006; 52: 68-74.
Tischler M. Platelet rich plasma. The use of autologous growth factors to enhance bone and soft tissue grafts. N Y State Dent J. 2002; 68: 22-24.
McAleer JP, Sharma S, Kaplan EM, Persich G. Use of autologous platelet concentrate in a nonhealing lower extremity wound. Adv Skin Wound Care. 2006; 19: 354-363.
Carrasco J, Bonete D, Gomar F. Plasma rico en plaquetas vs. plasma rico en factores de crecimiento. Revista Española de Cirugía Osteoarticular. 2009; 239: 127-137.
Fernández-Barbero JE, Galingo-Moreno P, Ávila-Ortiz G, Caba O, Sánchez Fernández E, Wang HL. Flow cytometric and morphological characterization of platelet-rich plasma gel. Clin Oral Implants Res. 2006; 17: 687-693.
Sánchez AR, Sheridan PJ, Kupp LI. Is platelet rich plasma the perfect enhancement factor? A current review. Int J Oral Maxillofac Implants. 2003; 18: 93-103.
Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost. 2004; 91: 4-15.
Anitua E, Azofra J, del Mar Zalduendo M, de la Fuente M. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cell in culture. J Orthop Res. 2005; 23: 281-286.
Lucarelli E, Beccheroni A, Donati D, Sangiorgi L, Cenacchi A, Del Vento AM et al. Platelet-derived growth factors enhance proliferation of human stromal stem cells. Biomaterials. 2003; 24: 3095-3100.
Crovetti G, Martinelli G, Issi M, Barone M, Guizzardi M, Campanati B et al. Platelet gel for healing cutaneous chronic wounds. Transfus Apher Sci. 2004; 30: 145-151.