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2010, Number 1

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Dermatología Cosmética, Médica y Quirúrgica 2010; 8 (1)

Hair’s molecular structure and development

Guzmán SDA, Alfaro AN, Sandoval-Tress C

Language: Spanish
References: 38
Page: 54-61
PDF size: 158.67 Kb.


ABSTRACT

The aim of the present article is to review the hair’s anatomy, histology, embriology, growth, and development. Also, we discuss molecular biology basic aspects and the molecular mechanisms regulating the hair’s morphogenesis and development.
Currently, it is necessary to know about the hair’s anatomy and molecular structure in order to design new treatments for alopecias. Hair loss affects most of the world population.


REFERENCES

  1. Paus R, Peker S, Sundberg JP. “Biology of hair and nails”. En Bolognia JL, Jorizzo JL, Rapini RP. Dermatology textbook, 2a ed., Londres, Mosby Elsevier, 2008, 965-1073.

  2. Restrepo R, McKee PH, Calonje E. “Diseases of the hair”. En McKee PH, Calonje E, Granter SR. Pathology of the skin with clinical correlations. Vol. 2, 3a ed., Londres, Mosby Elsevier, 2005, 1061-1126.

  3. Loomis CA, Koss T, Chu D. “Embriology”. En Bolognia JL, Jorizzo JL, Rapini RP. Dermatology textbook. 2a ed., Londres, Mosby Elsevier, 2008, 37-47.

  4. Jahoda CAB, Horne KA, Olivier RF. “Induction of hair growth by implantation of cultured dermal papilla cells”. Nature 1984; 311: 560-562.

  5. Reynolds AJ, Lawrence X, Csehalmi-Friedman PB et al. “Trans-gender induction of hair follicles”. Nature 1999; 402: 33-34.

  6. Link RE, Paus R, Stenn KS et al. “Epithelial growth by rat vibrissae follicles in vitro requires mesenchymal contact via native extracellular matrix”. J Invest Dermatol 1990; 95: 202-207.

  7. Nowak JA, Polak L, Pasolli HA, Fuchs E. “Hair follicle stem cells are specified and function in early skin morphogenesis”. Cell Stem Cell 2008; 3(1): 33-43.

  8. Richardson GD, Bazzi H, Fantauzzo KA, Waters JM, Crawford H, Hynd P et al. “KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin”. Development 2009; 136(13): 2153-2164.

  9. Moore KL. Persaud TVN. The developing human: Clinically oriented embryology. 7a ed., Filadelfia, Saunders Elsevier, 2003, 485-500.

  10. Millar SE. “Molecular mechanisms regulating hair follicle development”. J Invest Dermatol 2002; 118: 216-225.

  11. Alonso L, Fuchs E. “The hair cycle”. J Cell Sci 2006; 119: 391-393.

  12. Paus R, Cotsarelis G. “The biology of hair follicles”. N Engl J Med 1999; 341: 491-497.

  13. Stenn KS. “Molecular insight into the hair follicle and its pathology: A review of recent developments”. Int J Dermatol 2003; 42:40-43.

  14. Lewin B. Genes IX. 1a ed., Sudbury, Massachusetts, Jones and Bartlett, 2008, 1-23, 151-187.

  15. Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H et al. “Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling”. Development 2009; 136: 367-372.

  16. Ellis T, Gambardella L, Horcher M, Tschanz S, Capol J, Bertram P et al. “The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle”. Genes Dev 2001; 15: 2307-2319.

  17. Headon DJ. “Ectodysplasin signaling in cutaneous appendage development: Dose, duration, and diversity”. J Invest Dermatol 2009; 129(4): 817-819.

  18. Fujimoto A, Ohashi J, Nishida N, Miyagawa T, Morishita Y, Tsunoda T et al. “A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia”. Hum Genet 2008; 124: 179-185.

  19. Cui CY, Kunisada M, Esibizione D, Douglass EG, Schlessinger D. “Analysis of the temporal requirement for eda in hair and sweat gland development”. J Invest J Invest Dermatol 2009; 129(4): 984-993.

  20. Lee TC, Threadgill DW. “Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor”. Genesis 2008; 47: 85-92.

  21. Nishikawa SI, Osawa M, Yonetani S, Torikai-Nishikawa S, Freter R. “Niche required for inducing quiescent stem cells”. Cold Spring Harb Symp Quant Biol 2008; 73: 67-71.

  22. Hayashi T, Cunningham D, Bermingham-McDonogh O. “Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti”. Dev Dyn 2007; 236: 525-533.

  23. Cai J, Lee J, Kopan R, Ma L. “Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation”. Dev Biol 2009; 326: 420-430.

  24. Sano S, Takeda J, Yoshikawa K, Itami S. “Tissue regeneration: Hair follicle as a model”. J Investig Dermatol Symp Proc 2001; 6: 43-48.

  25. Tian T, Fan WX, Dai YQ, Liu LP. “Effect of tacrolimus on the growth cycle of murine hair follicles”. Pubmed 2007; 29(2): 209-212.

  26. Potter CS, Peterson RL, Barth JL, Pruett ND, Jacobs DF, Kern MJ et al. “Evidence that the satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation”. J Biol Chem 2006; 281: 29245-29255.

  27. Jang JH. “Stimulation of human hair growth by the recombinant human keratinocyte growth factor-2 (KGF-2)”. Biotechnol Lett 2005; 27: 749-752.

  28. Roel G, Gent YY, Peterson-Maduro J, Verbeek FJ, Destree O. “Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis”. Int J Dev Biol 2009; 53: 81-89.

  29. Mannini L, Deri P, Gremigni V, Rossi L, Salvetti A, Batistoni R. “Two msh/msx-related genes, Djmsh1 and Djmsh2, contribute to the early blastema growth during planarian head regeneration”. Int J Dev Biol 2008; 5(2): 943-952.

  30. Ito T, Ito N, Saatoff M, Hashizume H, Fukamizu H, Nickoloff BJ et al. “Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack”. J Invest Dermatol 2008; 128: 1196-1206.

  31. Hashimoto T, Schlessinger D, Cui CY. “Troy binding to lymphotoxinalpha activates NF kappa B mediated transcription”. Cell Cycle 2008; 7(1): 106-111.

  32. Tomita Y, Akiyama M, Shimizu H. “PDGF isoforms induce and maintain anagen phase of murine hair follicles”. J Dermatol Sci 2006; 43(2): 105-115.

  33. Adly MA, Assaf HA, Hussein MR. “Expression pattern of p75 neurotrophin receptor protein in human scalp skin and hair follicles: Hair cycledependent expression”. J Am Acad Dermatol 2009; 60(1): 99-109.

  34. Lehman JM, Laag E, Michaud EJ, Yoder BK. “An essential role for dermal primary cilia in hair follicle morphogenesis”. J Invest Dermatol 2009; 129(2): 438-448.

  35. Downes M, François M, Ferguson C, Parton RG, Koopman P. “Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation”. Hum Mol Genet 2009; 18(15): 2839-2850.

  36. Huh S, Lee J, Jung E, Kim SC, Kang JI, Lee J, Kim YW, Sung YK, Kang HK, Park D. ìA cell-based system for screening hair growth-promoting agents”. Arch Dermatol Res 2009; 301(5): 381-385.

  37. Plikus MV, Widelitz RB, Maxson R, Chuong CM. ìAnalyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity”. Int J Dev Biol 2009; 53(5-6): 857-868.

  38. Widelitz RB. “WNT signaling in skin organogenesis”. Organogenesis 2008; 4(2): 123-133.




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