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2014, Number 3

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Revista del Hospital Psiquiátrico de La Habana 2014; 11 (3)

Neuropsychological findings in patients with glioma. CIMEQ – 2013

Rodríguez PD, Figueredo MJ, Cueto MA, Fernández FS, Arreguín AI, Martínez FZ

Language: Spanish
References: 24
Page:
PDF size: 185.98 Kb.


ABSTRACT

Introduction: About 50 and 80% of patients with glioma presented cognitive alterations that significantly deteriorate his/her quality of life.
Objective: To determine the influence of glioma on the neuropsychological achievement.
Materials and Methods: The neuropsychological assessment in the upset of the disease and before surgery; on patients assisted at CIMEQ Hospital during the period January-December 2013. These patients fulfilled the criterions of inclusion. The sample included 27 patients. There were analyzed socialdemographic variables such as age, sex, and scholar level and clinical variables like affected hemisphere, and histology of the lesion on the neuropsychological achievement.
Results: According to sex, the distribution was different (male 63%, female 37%) with an age percentage of 45=15, 3 years. The located lesions in the frontal lobule (51%) were the most frequent, meanwhile the distribution according the the affected hemisphere were similar. In comparison to the general population, alterations in the majority of the functions were, as well as, slowing on the information process speed observed. The patients with lesions located on the right hemisphere presented problems with the visuoconstructive abilities. The patients with low level of glioma showed better achievement in attention and memory tasks. Age was as a variable that affects the neuropsychological achievement identified, which explains the difference in relation to the information process speed.
Conclusions: The existence of affectation was on multiple cognitive aspects on patients with glioma showed.


REFERENCES

  1. Peterson K. Brain tumors. Neurologic Clinics. 2001; 19: 887-902.

  2. Karim A, Laws E. Gliomas: Principles and Practice in Neuro- Oncology. Ed: Springer Verlag, Heidelberg, 1991.

  3. Levin V, Kyristis A. Gliomas, medulloblastomas, and CNS germ cell tumors. En F Cavalli, H Hansen (Eds.) Textbook of Medical Oncology, London: Martin Dunitz, the treatment of low-grade gliomas. Seminars in oncology. 2000; 6(l9): 45-8.

  4. Alvarán L, Gómez L, Ortíz, L, Aguirre D, Pineda D. Caracterización neuropsicológica de pacientes con glioma del Instituto de Cancerología de Medellín. Acta Neurol Colomb. 2007: 23(2), 58-70.

  5. Bondy M, Scheurer M, Malmer B, Barnholtz J, Davis F, Il’yasova D, Buffler P. On behalf of the Brain Tumor Epidemiology Consortium. Brain Tumor Epidemiology: Consensus from the brain tumor epidemiology consortium. Cancer. 2008; 113 (7):1953–68.

  6. Gil JL, Nieto A, Rodríguez JF, Almarcha J. Allelic loss at 1p/19q analysis in brain tumors of glial lineage. 2007. Neurocirugía. [Internet]. [Citado: Enero/2014] Disponible en:http://www.ncbi.nlm.nih.gov/pubmed/17882335

  7. Anuario Estadístico de Salud 2013. La Habana, 2014. [Internet]. [Citado: Enero/2014] Disponible en: http://www.infomed.sld.cu/sitios/dne/

  8. Vega AM, Rodríguez MI, Wilkinson B, Fernández A. Tumores astrocíticos: un acercamiento a una patología. Rev Méd Electrón. 2012; 34(3). [Internet] [Citado: Octubre/2014] Disponible en:http://www.revmatanzas.sld.cu/revista%20medica/ano%202012/vol3%202012/tem a10.htm

  9. Ropper A, Samuels M. Adams & Victor’s Principles of Neurology. New York: The McGraw-Hill Companies, Inc. 2009.

  10. Pérez L, Rodríguez E, Figueredo R, Barroso E. Astrocitoma anaplásico y glioblastoma multiforme. Factores que influyen en la supervivencia. Rev Cubana Cir. 2001; 40(2).

  11. Habets EJ, Kloet A, Walchenbach R, Vecht CJ, Klein M, Taphoorn MJ. Tumour and surgery effects on cognitive functioning in high-grade glioma patients. Acta neurochirurgica. 2014;156 (8):1451-9.

  12. Ardila A, Ostrosky F. Guía para el diagnóstico neuropsicológico. México DF. Universidad Autónoma de México, 2012.

  13. Ardila A, Ostrosky F. Diagnóstico del daño cerebral. México: Trillas, 1993.

  14. Wechsler D. WMS-R: Wechsler Memory Scale-Revised (Manual) San Antonio, The Psychological Corporation, 1987.

  15. Peña J. Programa Integrado de Exploración Neuropsicológica “Test de Barcelona”. Barcelona, España: Masson, S. A. 1990.

  16. Ardila A, Rosselli M. Neuropsicología clínica. Medellín: Prensa Creativa, 1992.

  17. Sanz A, Olivares M, Barcia J. Aspectos neuropsicológicos en pacientes diagnosticados de tumores cerebrales. Clínica y Salud. 2011; 22(2):139-55.

  18. Ek L, Almkvist O, Wiberg MK, Stragliotto G, Smits A. Early cognitive impairment in a subset of patients with presumed low-grade glioma. Neurocase. 2010;16(6):503-11.

  19. Tucha O, Smely C, Preier M, Lange K. Cognitive deficits before treatment among patients with brain tumors. Journal Neurosurgery. 2000; 47: 324-34.

  20. Mattavelli G, Casarotti A, Forgiarini M, Riva M, Bello L, Papagno C. Decision-making abilities in patients with frontal low-grade glioma. J Neurooncol. 2012;110(1):59-67.

  21. Sheibel R, Meyers C, Levin V. Cognitive dysfunction following surgery for intracerebral glioma: influence of histopathology, lesion location, and treatment. Journal Neurooncology. 1995; 3:265-70.

  22. Meyers C, Hess K, Yung W, Levin V. Cognitive function as a predictor of survival in patients with recurrent malignant glioma. Journal Clinical Oncology. 2000; 18:646-50.

  23. Bosma I, Vos M, Heimans J, Taphoorn M, Aaronson N, Postma T, et al. The course of neurocognitive functioning in high-grade glioma patients. Neuro-oncol. 2007; 9: 53–62.

  24. Noll KR, Sullaway C, Ziu M, Weinberg JS, Wefel JS. Relationships between tumor grade and neurocognitive functioning in patients with glioma of the left temporal lobe prior to surgical resection. Neuro-oncology. 2014.




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