2014, Number s1
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Gac Med Mex 2014; 150 (s1)
Polypharmacy prevalence and potentially inappropriate drug prescription in the elderly hospitalized for cardiovascular disease
Martínez-Arroyo JL, Gómez-García A, Sauceda-Martínez D
Language: Spanish
References: 36
Page: 29-38
PDF size: 241.40 Kb.
ABSTRACT
Introduction: Many older adults have multiple medical conditions that require medical attention, exposing them to
polypharmacy and to a higher increase in prescribing potentially inappropriate medications. These situations may cause
adverse drug reactions, longer hospital stays, and death. The prevalence of polypharmacy in our country is estimated
at 55% and inappropriate prescribing of medications of 30%.
Objective: To determine the prevalence of polypharmacy
and potentially inappropriate drug prescription in older patients hospitalized for cardiovascular diseases.
Material
and methods: Patients older than 70 years from a tertiary level hospital admitted to cardiology and angiology were
included, from the period 2013-2014. Fragility status, polypharmacy, and drug prescription based on the Beer’s criteria
were established. The results were analyzed using descriptive statistics. For inferential analysis, cross tabulations
with Pearson χ
2 were used.
Results: 446 patients where included, with female predominance of 56% (mean age 76.6
± 5.9 years). The prevalence of fragility was 35.7%, polypharmacy 84.5%, and inappropriate prescription of drugs 48.9%.
Coefficient correlation between inappropriate prescription of drugs and polypharmacy was p = 0.001.
Conclusions:
The prevalence of polypharmacy and inappropriate prescription of drugs was higher than reported previously, which
shows the situational diagnosis in this tertiary level hospital, considering a population with high cardiovascular risk.
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