2004, Number 1
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Rev Med Inst Mex Seguro Soc 2004; 42 (1)
Experience in treatment of myocadial infarction in the intensive care unit
Salazar WE
Language: Spanish
References: 33
Page: 61-67
PDF size: 67.03 Kb.
ABSTRACT
We carried out a revision of 305 records of patients
with acute myocardial infarction treated with three
different drugs. We analyzed effectiveness of each
on decreasing complications and mortality. Clinical
diagnosis was confirmed by electrocardiogram
and laboratory test of creatininekinase and MB
isoenzyme. We used Killip and Kimbal class to
stratify infarction and number of leads affected
with segment ST elevation to assess size. We observed
better evolution in patients treated with
streptokinase because they showed fast decrease
of angor pain and ST segment elevation. However,
these patients had bleeding, arterial hypotension,
and other complications. Unfractionated heparin
showed low effectiveness due to shortage of effects
in coronary thrombus; these patients underwent
major, long-term bleeding complications with angor
pain. This group had highest mortality. Enoxaparin
showed better effectiveness due to antithrombotic
activity and some thrombolytic capacity allowed
better patient evolution, decreasing complications
and mortality.
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