2014, Number 6
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Rev Med Inst Mex Seguro Soc 2014; 52 (6)
Disseminated intravascular coagulation. Case series and literature review
del Carpio-Orantes L, García-Ortiza JJ
Language: Spanish
References: 10
Page: 680-683
PDF size: 54.86 Kb.
ABSTRACT
Background: Disseminated intravascular coagulation is an entity characterized
by activation of the coagulation cascade and endogenous
fibrinolysis, which can cause death. Our objectives were to identify the
incidence of disseminated intravascular coagulation, its etiologic agents
and the correlation between the Apache II score and the one proposed
by the International Society on Thrombosis and Haemostasis for the
diagnosis of this entity.
Methods: Retrospective, descriptive, observational study of patients
treated in an intensive care unit over a 17-month period. Etiology,
age, sex, platelet count, coagulation tests, serum fi brinogen levels and
D-dimer quantifi cation were analyzed. The score on the scale proposed
by the International Society on Thrombosis and Haemostasis and the
Apache II score were calculated.
Results: 11 patients (7.18 % of the total number treated subjects at
the intensive care unit) had a diagnosis of disseminated intravascular
coagulation; six were females. Sepsis was the main etiologic agent (four
cases). The most affected age group was the 51-60 years group (four
cases). The prognosis was bad in seven subjects. Patients with fi ve
points or more in the DIC system, but with a low Apache II score had a
good prognosis.
Conclusions: The combination of the DIC and the Apache II scores
serves for predicting the outcome of patients with severe organ injuries.
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