2014, Number 4
<< Back Next >>
Rev Mex Angiol 2014; 42 (4)
El diagnóstico de pileflebitis por imagen seccional
Motta-Ramírez GA, González-Burgos O, Martínez-Utrera MJ, Luján-Cortés EI, García-Ruiz A, Ordóñez-Gutiérrez M
Language: Spanish
References: 49
Page: 150-162
PDF size: 341.44 Kb.
ABSTRACT
Introduction. Pylephlebitis or septic thrombophlebitis of the portal vein is a serious condition
with significant morbidity and mortality. It is a rare but serious condition complication of intra-abdominal
infection that occurs in the region drained by the portal venous system. The diagnosis of
pylephlebitis requires the demonstration of a portal vein thrombosis usually accompanied by bacteremia
in a febrile patient. Diagnosis is often difficult since no specific clinical signs, symptoms
and laboratory parameters are involved. This may lead to a delay in treatment. Pylephlebitis is a
condition with significant morbidity and mortality. The most common predisposing infections leading
to pylephlebitis were appendicitis and diverticulitis.
Material and methods. Retrospective review of 9 years and 8 months with clinic-tomographic-pathologic
correlation including 17 patients with pylephlebitis.
Results. A precipitating focus of infection (most commonly appendicitis) was identified in 6 (35%)
of the cases. Pylephlebitis is a likely cause of hepatic abscess (47%); multiple (18%). More abscesses
occur in the right than in the left lobe. Thrombosis was extended to branches of the portal vein
in 16 (94%) and to the superior mesenteric vein, splenic vein, and intrahepatic in 8 (47%); in 13
(76%) a nonneoplastic hepatic vascular perfusion disorder was identified and in 2 (12%) vascular
intraluminal gas was identified.
Conclusions. Pylephlebitis which may be difficult to diagnose even with imaging techniques such
as CT scan. It should be considered in patients with sepsis due to gut-associated organisms
without a clear source of infection. pylephlebitis remains an entity with high morbidity and mortality,
but modern imaging modalities have facilitated an earlier diagnosis and have improved the
prognosis. While diverticulitis is thought to be the leading cause of this disease, in our study appendicitis
and cholecystitis occurs frequently, and various other suppurative intra-abdominal infections.
REFERENCES
Menéndez-Sánchez P, Gambí-Pisonero D, Villarejo- Campos P, Padilla-Valverde D, Martín-Fernández J. Tromboflebitis séptica de la vena porta secundaria a colecistitis aguda. Cir Cir 2010; 78: 439-41.
Gnocchi CA, Sánchez C, Santamarina J, Risso J, Mazzocchi O, Bruguera C. Tromboflebitis séptica de la vena porta asociada a hipertensión portal reversible. Medicina (Buenos Aires) 2001; 61: 855-9.
Wireko M, Berry PA, Brennan J, Aga R. Unrecognized pylephlebitis causing life-threatening septic shock: A case report. World J Gastroenterol 2005; 11(4): 614-5.
Tandon R, Davidoff A, Worthington MG, Ross JJ. Pylephlebitis after CT-guided percutaneous liver biopsy. AJR 2005; 184: S70-S72.
Garrett A, Carnish E, Das N, Slome M, BA, Measley R. Once Universally Fatal: Pylephlebitis. Am J Med 2014; 127(7): 595-7.
Wong K, Weisman DS, Patrice KA. Pylephlebitis: a rare complication of an intra-abdominal infection. Journal of Community Hospital Internal Medicine Perspectives 2013; 3: 20732. Disponible en: http://dx.doi.org/10.3402/ jchimp.v3i2.20732
Altamirano J, Zapata L, Poblano M, Rodríguez A, Camargo L, Martínez B, et al. Acute pylephlebitis following gastrointestinal infection: An unrecognized cause of septic shock. Southern Medical Journal 2010; 103(9): 956-9.
Hagopian, Tara H, Zuniga F, Salim RS. Pylephlebitis: An uncommon complication of intra-abdominal infection. Western Journal of Emergency Medicine 2011; 12(4): 575-6.
Soto Sánchez A, Sánchez González JM, Hernández M, Soriano Benítez de Lugo A. Pileflebitis: complicación infrecuente de la colecistitis aguda. Span J Surg Res 2013; XVI(2): 81-2.
Álvarez-Blanco M, Rodrigo del Valle-Ruiz S, González González JJ, Hernández-Luyando L, Martínez-Rodríguez E. Pileflebitis tras apendicitis aguda. Rev Esp Enferm Dig (Madrid) 2007; 99(1): 49-50.
Subercaseaux VS, Zúñiga RS, Encalada AR, Zúñiga CP, Berrríos GC. Pileflebitis asociada a apendicitis aguda en una niña de 11 años. Rev Chilena de Cirugía 2010; 62(2): 160-4.
Soo Chang Y, Young Min S, Hyung Joo S, Suk-Hwan L. Septic thrombophlebitis of the porto-mesenteric veins as a complication of acute appendicitis. World J Gastroenterol 2008; 14(28): 4580-2.
Kykalos S, Sotiropoulos GC, Vernadakis S. Septic mesenteric venous thrombophlebitis: A rare complication of acute appendicitis. Case Reports in Medicine Volume 2011, Article ID 858563, 2 pages. Doi:10.1155/2011/ 858563.
Coyne CJ, Jain A. Pylephlebitis in a previously healthy emergency department patient with appendicitis. West J Emerg Med 2013; 14(5): 428-30.
Waxman BP, Cavanagh LL, Nayman J. Suppurative pylephlebitis and multiple hepatic abscesses with silent colonic diverticulitis. Med J Aust 1979; 2: 376-8.
Gajendran M, Muniraj T, Yassin M. Diverticulitis complicated by pylephlebitis: a case report. Journal of Medical Case Reports 2011, 5: 514. Disponible en: http:// www.jmedicalcasereports.com/content/5/1/514
Van De Wauwer C, Irvin TT. Pylephlebitis due to perforated diverticulitis. Acta Chir Belg 2005; 105: 229-30.
Yu JS, Bennett WF, Bova JG. CT of superior mesenteric vein thrombosis complicating periappendiceal abscess. JCAT 1993; 17: 309-12.
Kanellopoulou T, Alexopoulou A, Theodossiades G, Koskinas J, Archimandritis AJ. Pylephlebitis: an overview of non-cirrhotic cases and factors related to outcome. Scand J Infect Dis 2010; 42(11-12): 804-11.
León Pacheco JC, Quiroga Vera JF. Pileflebitis: Presentación de un caso y revisión bibliográfica. Med Hoy 2007; 23(1): 42-5.
Falkowski AL, Cathomas G, Zerz A, Rasch H, Tarr PE. Pylephlebitis of a variant mesenteric vein complicating sigmoid diverticulitis. Radiology Case 2014; 8(2): 37-45.
Tsao YT, Lin SH, Cheng CJ, Chang FY. Pylephlebitis associated with acute infected choledocholithiasis. Am J Med Sci 2006; 332: 85-7.
Baddley JW, Singh D, Correa P, Persich NJ. Crohn’s disease presenting as septic thrombophlebitis of the portal vein (pylephlebitis): case report and review of the literature. Am J Gastroenterol 1999; 94: 847-9.
Aguas M, Bastida G, Nos P, Beltrán B, Grueso JL, Grueso J. Septic thrombophlebitis of the superior mesenteric vein and multiple liver abscesses in a patient with Crohn’s diseases at onset. BMC Gastroenterology 2007; 7: 22. Doi:10.1186/1471-230X-7-22
Hamouda NH, Grothe RM, Ibrahim SH. Multiple liver lesions in an immunosuppressed patient: Is infection always the answer? Case Rep Gastroenterol 2013; 7: 327-31.
Tung JY, Jeffrey LJ, Liacouras CA. Portal-mesenteric pylephlebitis with hepatic abscesses in a patient with Crohn’s disease treated successfully with anticoagulation and antibiotics. J Pediatr Gastroenterol Nutr 1996; 23(4): 474-8.
López-Rodríguez R, Martínez-Rey C, Campos-Franco J, Alende-Sixto MR, Torre-Carballada JA. Pileflebitis idiopática en paciente con mutación del factor V Leiden. Cartas al director. An Med Interna (Madrid) 2006; 23(7): 350-1.
Chau NG, Bathia S, Raman M. Pylephlebitis and pyogenic liver abscesses: a complication of hemorroidal banding. Can J Gastroenterol 2007; 21: 601-3.
Núñez-Delgado Y, López-Martin G, Eisman-Hidalgo M. Pileflebitis tras CPRE. RAPD On line 2014; 37(2): 111-3.
De Roover A, Detry O, Coimbra C, Hamoir E, Honoré P, Meurisse M. Pylephlebitis of the portal vein complicating intragastric migration of an adjustable gastric band. Obes Surg 2006; 16: 369-71.
Rimsky-Álvarez U, Roberto-González L, Galia-Gutiérrez J. Tromboflebitis séptica de la vena porta. Rev Chilena de Cirugía 2002; 54(6): 676-80.
Spelman D. Pylephlebitis. UpToDate, Inc Web site. Disponible en: http:// www.uptodate.com/online/content/ topic.do?topicKey¼gi_infec/7960&selectedTitle¼1; 7&source¼search_result [Accessed July 13, 2014].
Hagopian T, Zuniga F, Surani SR. Pylephlebitis: An uncommon complication of intra-abdominal infection. West J Emerg Med 2011; 12(4): 575-6.
Balthazar EJ, Gollapudi P. Septic thrombophlebitis of the mesenteric and portal veins: CT imaging. JCAT 2000; 24: 755-60.
Domínguez-Vargas R, Balcázar-Vázquez R, Rodríguez- Blas AI, Casian-Castellanos GA. Pileflebitis como complicación del proceso inflamatorio abdominal. Rev Hosp Jua Mex 2012; 79(1): 48-50.
Motta-Ramírez GA. Online slideshare, LinkedIn Corporation © 2014, Diagnóstico incidental de trombosis abdominopélvica por tomografía computada multidetector. Disponible en: http://www.slideshare. net/betomotta/ diagnostico-incidental-de-trombosis-abdominopelvicapor- tomografia-computada-multidetector-tcmd (Consultado: agosto 27, 2014).
Motta-Ramírez GA. Online slideshare, LinkedIn Corporation © 2014, El radiólogo y la trombosis abdominopélvica por tomografía computada multidetector. Disponible en: http://www.slideshare.net/betomotta/el-radilogo-y-latrombosis- abdomino-plvica-por-tcmd-7874109 (Consultado: agosto 27, 2014)
Sebastià C, Coll D, Mauleon S, Sanz P, Allende E, Miranda A. Pileflebitis secundaria a perforación de divertículo ileal. Radiología 2004; 46(3): 179-81.
Liappis AP, Roberts AD, Schwartz AM, Simon GL. Thrombosis and infection: a case of transient anti-cardiolipin antibody associated with pylephlebitis. Am J Med Sci 2003; 325: 365-8.
Heller MT, Bhargava P. MDCT of acute cecal conditions. Emer Radiol 2014; 21: 75-82.
Motta-Ramírez GA, González-Burgos OM, Quiroz-Castro O. Diagnóstico incidental de trombosis abdominopélvica por Tomografía Computada multidetectores. An Radiol Mex 2007; 6(2): 97-112.
Quintero GA. Guías para manejo de urgencias: Pileflebitis.
Brown KT, Gandhi RT, Covey AM, Brody LA, Getrajdman GI. Pylephlebitis and liver abscess mimicking hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int 2003; 2(2): 221-5.
García-Figueiras R, Liñares-Paz M, Baleato-González S, Villalba-Martín C. Case 158: Pylephlebitis. Radiology 2010; 255: 1003-7.
McGinty R, Javaid B. Pylephlebitis in a 58-year-old man. Gastroenterology Today 2011; 21(3): 56-8.
Singh P, Yadav N, Visvalingam V, Indaram A, Bank S. Pylephlebitis-diagnosis and management. Am J Gastroenterol 2001; 96: 1312-3.
Pérez-Aisa Á, Rosales-Zábal JM. Pileflebitis. GH Continuada 2011; 10(5): 246-9.
Stitzenberg KB, Piehl MD, Monahan PE, Duncan PJ. Interval laparoscopic appendectomy for appendicitis complicated by pylephlebitis. JSLS 2006; 10: 108-13.
Duffy FJ Jr, Millan MT, Schoetz DJ Jr, Larsen CR. Suppurative pylephlebitis and pylethrombosis: The role of anticoagulation. Am Surg 1995; 61: 1041-4.