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2013, Number 2

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Dermatología Cosmética, Médica y Quirúrgica 2013; 11 (2)

Dermatitis herpetiformis with immunofluorescent fibrillar pattern: Case report and literature review

López ZJB, Romo SC

Language: Spanish
References: 31
Page: 112-116
PDF size: 182.36 Kb.


ABSTRACT

Dermatitis herpetiformis (DH) is a rare blistering, autoimmune disease of multifactorial etiology, deemed to be a cutaneous manifestation of dietary gluten hypersensitivity. Direct immunofluorescence (DIF) of perilesional skin usually reveals a granular pattern in the upper papillary dermis or the basal membrane. However, there are reports of a rare fibrillar pattern that has been associated with atypical DH presentations, negative serology and even absence of the of HLA-B8/DR3DQ2 haplotype. This is a report of a typical DH case with fibrillar DIF findings, including a brief review of existing literature.


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