2013, Número 2
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Dermatología Cosmética, Médica y Quirúrgica 2013; 11 (2)
Dermatitis herpetiforme con patrón fibrilar en inmunofluorescencia: reporte de un caso y revisión de literatura
López ZJB, Romo SC
Idioma: Español
Referencias bibliográficas: 31
Paginas: 112-116
Archivo PDF: 182.36 Kb.
RESUMEN
Dermatitis herpetiforme (DH) es una rara enfermedad ampollar
autoinmune, de etiología multifactorial, que suele considerarse
una manifestación cutánea de hipersensibilidad al gluten dietético.
En su abordaje diagnóstico figura la inmunofluorescencia
directa (IFD) de piel perilesional, típicamente con patrón granular
en papilas o membrana basal. Sin embargo, también se ha
descrito un patrón fibrilar relativamente raro que suele relacionarse
con una presentación atípica de la enfermedad, seronegatividad
en pruebas de anticuerpos e incluso ausencia de haplotipo
HLA-B8/DR3DQ2. Este artículo describe un caso DH típico con
IFD en patrón fibrilar y hace una breve revisión de la literatura.
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