Herrera PM, Ruiz PS, Hamilton HRL, Camacho RRI, Velázquez QNI, Ávila RR

Language: Spanish
References: 15
Page: 92-96
PDF size: 260.56 Kb.

ABSTRACT

Introduction: Neonatal hyperthiroidism linked to maternal Graves disease is considered as Neonatal Graves disease and is characterized by elevated T4 and T3 thyroid hormones and lack of TSH. It has maternal, fetal and neonatal effects. Among the outstanding clinical data are goiter, exophtalmos, intrauterine growth restriction, tachycardia and heart failure. We report a case of neonatal Graves disease.
Clinical case: Female newborn, mother with Graves disease diagnosed in the third trimester of pregnancy. Born at 34 weeks gestation weighing 1,600 g, height 40 cm. Newborn clinical signs were exophthalmos, goiter, congenital heart disease IVC type, intrauterine growth restriction, tachycardia progressing to heart failure and cerebral ventricular dilatation. Low TSH and elevated fT4. Treated with digoxin, propranolol and methimazole. Discharged in good general health and fT4 decreasing.
Discussion: The current case of neonatal Graves disease is very similar to that described in the literature from maternal history and clinical presentation. It is necessary to keep the mother euthyroid during the gestational period, otherwise, it could be fatal. The pregnant women with hyperthyroidism must be closely monitored before, during and after pregnancy. Certain cases require no treatment because hyperthyroidism is transient. In cases that require treatment with antithyroid drugs should be periodically monitored TSH, T3 and T4 levels in the neonate.

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