2013, Number 3
<< Back Next >>
Pediatr Mex 2013; 15 (3)
Validity of otoacoustic emissions to detect hearing loss in high-risk neonates
González-Amaro C, Reyna-Barrientos M, Hernández-Sierra F, Suárez-Llanas B, Torres-Carreón F, Escalante-Padrón F
Language: Spanish
References: 22
Page: 80-83
PDF size: 126.92 Kb.
ABSTRACT
Hearing loss in newborns (NB) has a frequency of 1-3/1,000, but is 20 times more frequent in graduates of Neonatal Intensive Care Units (NICU), so their detection is a priority.
Objective: To determine the sensitivity, specificity and predictive values of otoacoustic emissions (OAE) to detect hearing loss in newborns at high risk of NICU graduates.
Methodology: Diagnostic test study. Neonatal hearing screening was performed (TAN) in a blinded fashion with OAE, 134 RN with risk factors at hospital discharge, and confirmatory test, auditory brainstem evoked potentials (ABEP) as a gold standard, at 3 months of corrected age.
Results: Hearing loss was found in 19 NB (14.17%), of these, 6 (4.47%) with bilateral profound hearing impairment. The sensitivity of the EOA was 19.23% (95%, CI 4.08 to 34.38); specificity of 98.74% (95%, CI 97.32 to 100); positive predictive value 62.50% (95%, CI 28.95 to 96.05) and negative predictive value 91.80% (95%, CI 88.44 to 95.16). Concordance of measurements was 100% with kappa.
Conclusions: The incidence of hearing loss of varying degrees was higher than that reported in the population of NICU graduates. In the population of graduates NICU infants studied the OAE obtained a very low sensitivity (19.23%) to detect hearing loss with a high rate (80.77) of false negatives. With these results it is confirmed that our population of Mexican infants with risk factors using the OAE as a single screening test in infants at high risk, because of the high possibility of false negatives and possible auditory neuropathy is not recommended. However NB healthy without risk factors, the OAE is still a good screening tool because of its high specificity and negative predictive value.
REFERENCES
Tippens PE. Física, conceptos y aplicaciones. 6ª ed. McGraw-Hill; 2001.
Peñaloza López YR, Castillo Maya G, Ruiz Bautista MA, García Pedroza F, Del Castillo Catalán M, García Sánchez G et al. Trastornos auditivos en el menor de tres años. México: Trillas; 2007: p. 160.
Secretaría de Salud, Subsecretaría de Prevención y Promoción de la Salud. Programa de acción específico 2007-2012: Tamiz auditivo neonatal e intervención temprana. México: Secretaría de Salud; 2008: p. 52.
Erenberg A, Lemons J, Sia C, Trunkel D, Ziring P. Newborn and infant hearing loss: Detection and intervention. Task force on newborn and infant hearing. Pediatrics. 1999; 103(2): 527-530.
Martínez-Cruz CF, Fernández-Carrocera LA, Ortigosa-Corona E. Perfil audiométrico del niño hipoacúsico egresado de una Unidad de Cuidado Intensivo Neonatal: análisis de 40 casos. Bol Med Hosp Infant Mex. 2000; 57(3): 140-148.
INEGI. Datos sociales demográficos y educacionales. [Internet]. México; 2003. Disponible en: http://www.inegi.org.mx/
Finitzo T, Albright K, O’Neal J. The newborn with hearing loss: detection in the nursery. Pediatrics. 1998; 102(6): 1452-1460.
Trinidad-Ramos G, Alzinade-Aguilar V, Jaudenes-Casaubon C, Núñez-Batalla F, Sequi-Canet JM. Recomendaciones de la Comisión para la Detección Precoz de la Hipoacusia (CODEPEH) para 2010. Acta Otorrinolaringol Esp. 2010; 61(1): 69-77.
Stevens Wrightson A. Universal Newborn Hearing Screening. Am Fam Physician. 2007; 75(9); 1349-1352.
Audiología Básica de Sebastián. Trillas; 1997.
American Academy of Pediatrics, Joint Committee on Infant Hearing. Year 2007 Position Statement: principles and guidelines for early hearing detection and intervention programs. Pediatrics. 2007; 120(4): 898-921.
Clemens CJ, Davis SA, Bailey AR. The false-positive in universal newborn hearing screening. Pediatrics. 2000; 106(1): E7.
Morales-Angulo C, Gallo-Terán J, Del Castillo I, Moreno-Pelayo MA. Características audiométricas de la hipoacusia familiar transmitida por herencia mitocondrial (A1555G). Acta Otorrinolaringol Esp. 2002; 53(9): 641-648.
Gallo-Terán J, Morales Angulo C, Del Castillo MI, Moreno-Pelayo MA, García-Mantilla J, Moreno F. Incidencia de las mutaciones A1555G en el ADN mitocondrial y 35del IG en el gen GJB2 (conexina 26) en familias con hipoacusia neurosensorial postlocutiva no sindrómica en Cantabria. Acta Otorrinolaringol Esp. 2002; 53: 563-571.
Dort JC, Tobolski C, Brown D. Screening strategies for neonatal hearing loss: wich test is best? J Otolaryngol. 2000; 29(4): 206-210.
Smyth V, McPherson B, Kei J, Young J, Tudehope D, Maurer M, Rankin G et al. Otoacustic emission criteria for neonatal hearing screening. Int J Pediatr Otorhinolaringol. 1999; 48(1): 9-15.
Mason JA, Herrman KR. Universal infant hearing screening by automated auditory branstem response measurement. Pediatrics. 1998; 101(2): 221-228.
Suppiej A, Rizzardi E, Zanardo V, Franzoi M, Ermani M, Orzan E. Reliability of hearing screening in high-risk neonates: comparative study of otoacoustic emission, automated and conventional auditory brainstem response. Clin Neurophysiol. 2007; 118(4): 869-876.
Morlet T, Ferber-Viart C, Putel G, Servin F, Duclaux R. Auditory screening in high-risk pre-term and full-term neonates using evoked otoacoustic emissions and brainstem auditory evoked potentials. Int J Padiatr Otorhinolaryngol. 1998; 45(1): 31-40.
Dort JC, Tobolski C, Brown D. Screening strategies for neonatal hearing loss: wich test is best? J Otolaryngol. 2000; 29(4): 206-210.
Wollf R, Hommerich J, Riemsma R, Antes G, Lange S, Kleijnen J. Hearing screening in newborns: systematic review of accuracy effectiveness, and effects of interventions after screening. Arch Dis Child. 2010; 95(2): 130-135.
Robertson CM, Howarth TM, Bork DL, Dinu IA. Permanent bilateral sensory and neural hearing loss of children after neonatal intensive care because of extreme prematurity: A thirty-year study. Pediatrics. 2009; 123(5); e797-807.