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2002, Number 2

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Anales de Radiología México 2002; 1 (2)

Clinical applications of Functional magnetic resonance

Salgado-Lujambio P, Delgado-Hernández R, Rojas-Jasso R, Sánchez-Cortazar J, Reynoso-Padilla G, Barrios FA

Language: Spanish
References: 140
Page: 431-446
PDF size: 466.56 Kb.


ABSTRACT

Traditionally all the studies of functional mapping in the central nervous system were done using nuclear medicine techniques, PET (Positron Emission Tomography) and SPECT (Single Photon Emission Computarized Tomography). The typical studies conducted with these techniques are applied to a variety of neuropathology cases that include; ischemia, neoplasia, epilepsy and neuro-degenerative diseases like Parkinson and Alzheimer.
At present time in magnetic resonance imaging there are techniques that have the potential to estimate brain function. Among them are diffusion imaging techniques sensitive to the Brownian motion in the tissue’s water molecules, which can evaluate dynamical changes due to hyperacute ischemic processes and in neoplasm formation. Perfusion imaging use an exogenous contrast agent to map the relative cerebral blood volume, the information provided by this technique can be used as complementary information in the evolution of acute ischemic events as well as in reincidence of neoplasic processes. Proton magnetic resonance spectroscopy can be used in metabolic behavior in vivo evaluation directly from cerebral parenchyma. Finally, dynamical t2* weighted imaging or BOLD (Blood Oxygenization Level Dependent) imaging is used in mapping the functional processes in different primary cortex of the human brain.


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