2005, Number 4
<< Back Next >>
Med Cutan Iber Lat Am 2005; 33 (4)
Erithrodermias. Clinical pathologycal retrospective study of 45 cases
Jaime R, Lagodín C, Dahbar M, Allevato M, Cabrera H, Devés A
Language: Spanish
References: 18
Page: 159-165
PDF size: 156.46 Kb.
ABSTRACT
The main purpose of our study wasto describe the causes, the clinical pathological correlation and the evolution of erithrodermias of our files and
to compare our data
with other series.
The planning of the study is retrospective, observable, descriptive and transversal.
Forty-five clinical histories, with the diagnosis of erithrodermia were analyzed; 27 patients corresponde to the outside consultation and 18 were
from our clinic, during period 1991-2002. The parameters studied were: age, sex, etiology, anatomia pathological changes anatomy, time of
duration, previous antecedents of erithrodermia and final evolution.
It was obtained a total of 45 clinical histories, corresponding 28 (62,2%) to males and 17 (37,8%) to females. The average age of presentation
was of 53,8 years. The etiology of erithrodermias was classified, initially in 4 groups, corresponding 28 (62%) to previous dermatosis, 9 (20%) to
drugs, 5 (11%) to neoplasias and 3 (7%) of unknown origin.
From the 45 clinical histories reviewed, the result was concludent in only 21 cases, after a second biopsy in 7 patients, it was possible to reach the
diagnosis of T-cell lymphoma in 3 patients (14%) increasing the initial number of 4 (19%) to 7 (33%).
In our the age average of presentation was 53,8 years, being prevalent in men´sevie (62%). The more frequent cause was a previous dermatosis
(62%) and within this group 68% belonged to psoriasis. The clinic-histopatological correlation was of 67% with the first biopsy, while the
effectiveness diagnostic increased in 95% with a second biopsy. The final evolution was favorable in 58%, unfavorable in 18% and unknow in
24% of the cases.
REFERENCES
Rook A, Wilkinson DS, Ebling EB. Eczema. Liquenification, Prurigo and Erythroderma. In: Champion RH, Burton JL, Ebling FJG, eds. Textbook of Dermatology, 5th edition. Oxford: Blackwell Scientific Publications, 1992.
Nicolis GD, Helwig EB. Exfoliative dermatitis: a clinicopathologic study of 135 cases. Arch Dermatol 1973;108:788-97.
Botella-Estrada R, Sanmartín O, Oliver V, Febrer I, Aliaga A. Erythroderma: A clinicopathological study of 56 cases. Arch Dermatol 1994;130:1503-7.
Zip C, Murray S, Walsh NMG. The specificity of histopathology in erythroderma. J Cutan Pathol 1993;20:393-8.
Abrahams I, McCarthy JT, Sanders SL. 101 cases of exfoliative dermatitis. Arch Dermatol 1963;87:96 -101.
Wilson HTH: Exfoliative dermatitis. Its etiology and prognosis. Arch Dermatol 1954;
69:577-88. 7. Sigurdsson V, Toonstra , van Vloten WA. Idiopathic erythroderma: a follow-up study of 28 patients. Dermatology 1997;194-8.
Hasan T, Jansen CT. Erythroderma: a followup of fifty cases. J Am Acad Dermatol 1983;8:836 -40.
Rothe M, MD, Bialy T. Erythroderma. Dermatol Clinics 2000;18:405-15.
Winkelmann RK, Buechner SA, Diaz-Perez JL: Pre-Sézary syndrome. J Am Acad Dermatol 1984;10:992-9.
Winkelmann RK, Caro WA. Current problems in mycosis fungoides and Sézary syndrome. Annu Rev Med 1977;28:251- 69.
Russell R, Whittaker S. Sézary Syndrome: Diagnostic criteria and therapeutic options. Sem Cut Med Surg. 2000;19:100 -8.
Lee NH, Lee S-W, Ahn SK.: A case of Pre-Sézary Syndrome preceded by hand lesions. J Dermatol 1999;26:465-8.
Febrer Bosch MI, Botella-Estrada R. Eritrodermias. Med. Cutan. Iber. Lat. Am. 1992;20:137-47.
Howard MS, Smoller BR. Mycosis Fungoides: Classic Disease and Variant Presentations. Sem Cut Med Surg. 2000;19,:91-9.
Sehgal V.N., Srivastava G. Exfoliative Dermatitis. A prospective study of 80 patients. Dermatologica 1986;173:278 -84.
Walsh N, Prokopetz R. Histopathology in erythroderma: review of a series of cases by multiple observers. J Cutan Pathol. 1994;21: 419-23.
Lever, Elder D.: Histopatología de la piel.8° edición. 1999;9:199-200.