2014, Number 1
<< Back Next >>
Rev Cub de Reu 2014; 16 (1)
Undifferentiated connective tissue disease associated with deficiency of IgG2 and IgG4
Saldarriaga RLM, Delgado QLA, Ríos GBBE
Language: Spanish
References: 12
Page: 47-51
PDF size: 409.28 Kb.
ABSTRACT
The undifferentiated connective tissue disease is a condition of unknown etiology that shares clinical, pathological and laboratory characteristics with several collagenases, without meeting the criteria of the American College of Rheumatology for the diagnosis of a specific rheumatic disease. The IgG subclass deficiency term refers to a significant decrease in serum concentrations of one or more IgG subclasses in a patient whose total IgG concentration is normal, presenting recurrent bronchitis, sinusitis or otitis. We report the case of a female patient diagnosed with undifferentiated connective tissue disease associated with deficiency of IgG2 and IgG4.
REFERENCES
McLean-Tooke A, Oʼsullivan M, Easter T, Loh R. Differences between total IgG and sum of the IgG subclasses in clinical samples. Pathology. 2013;45(7):675-7.
Azar AE, Ballas ZK. Evaluation of the adult with suspected immunodeficiency. Am J Med. 2007;120(9):764-8.
Martinot M, Oswald L, Parisi E, Etienne E, Argy N, Grawey I, et al. Immunoglobulin deficiency in patients with Streptococcus pneumoniae or Haemophilus influenzae invasive infections. Int J Infect Dis. 2013;7(13):350-1
Herrod HH. Management of the patient with IgG subclass deficiency and/or selective antibody deficiency. Ann Allergy. 1993;70(1):3-8.
Doria A, Mosca M, Gambari PF, Bombardieri S. Defining unclassifiable connective tissue diseases: incomplete, undifferentiated, or both. J Rheumatol. 2005;32(2):213-15.
Mosca M, Tani C, Neri C, Baldini C, Bombardieri S. Undifferentiated connective tissue diseases (UCTD). Autoimmun Rev. 2006;6(1):1-4.
Alarcón GS, Willkens RF, Ward JR, Clegg DO, Morgan JG, Ma KN, Yarboro, C. Early undifferentiated connective tissue disease. Musculoskeletal manifestations in a large cohort of patients with undifferentiated connective tissue diseases compared with cohorts of patients with well-established connective tissue diseases: followup analyses in patients with unexplained polyarthritis and patients with rheumatoid arthritis at baseline. Arthritis & Rheumatism. 1996;39(3):403-14.
Mosca M, Tani C, Neri C, Baldini C, Bombardieri S. Undifferentiated connective tissue diseases (UCTD). Autoimmunity reviews. 2006;6(1):1-4.
Kallenberg CG. Early detection of connective tissue disease in patients with Raynaud's phenomenon. Rheum Dis Clin North Am. 1990;16(1):11-30.
Kay RA, Wood KJ, Bernstein RM, Holtand PJL, Humphrey RSH. An IgG subclass imbalance in connective tissue disease. Ann Rheum Dis. 1988;47(7):536-38.
Cataldo F, Paternostro D. IgG subclasses and their clinical significance. Minerva Pediatr. 1990;42(12):509-14.
Racanelli V, Prete M, Musaraj G, Dammacco F, Perosa F. Autoantibodies to intracellular antigens: generation and pathogenetic role. Autoimmunity reviews. 2011;10(8):503-08.