2014, Number 2
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Rev Cubana Plant Med 2014; 19 (2)
Evaluation of the antimicrobial and modulating activity of hexane extract from Costus cf. ArabicusL.
Sobral SCE, Figueiredo LN, Vieira BDI, Batista ALB, Lima SLAK, Ferreira MEF, Sabino AR, de Alencar FJV, Bezerra CFA, Relison TS, Martins CJG, Melo CHD
Language: Portugués
References: 34
Page: 151-159
PDF size: 118.70 Kb.
ABSTRACT
Introduction: Pseudomonas aeruginosa is known to cause acute infection due to
the production of toxins. Some specimens of
Staphylococcus are often recognized
as the etiologic agents of opportunistic infections in many animals and humans.
Escherichia coli is a leading cause of human infectious diseases. The genus
Candida
produces several virulence factors. Infections are probably initiated by changes in
host defenses.
Objective: evaluate the antimicrobial effect of hexane extract of
Costus cf. and
themodulation of
Costus cf.
Arabicus. L. antibiotic activity.
Methods: botanical material from
Costus cf.
arabicus L. was collected at Crato,
Ceará, Brazil. For the preparation of extracts fresh leaves and stems were collected, separately immersed in hexane for 72 hours, and thereafter filtered and
concentrated in a rotary vacuum condenser. Tests of antimicrobial activity (MIC)
and antimicrobial activity modulation were conducted with multiresistant strain
patterns of bacteria and fungi.
Results: the extract showed antibacterial and antifungal activity against some of
the strains tested when combined with some antibiotics.
Conclusions: therefore, it is suggested that the extract of
Costus cf. be used as a
source of natural products for antimicrobial therapy and to combat bacterial and
fungal multidrug resistance.
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