2005, Number 1
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Med Cutan Iber Lat Am 2005; 33 (1)
Cocaine and Ergotamine Vasospasm in a HIV Patient
Bourren P, Rodríguez EA, Mijelshon LM, Kujaruk M
Language: Spanish
References: 17
Page: 31-33
PDF size: 228.82 Kb.
ABSTRACT
Cocaine is a widespread alkaloid, that consumers usually prefer as a stimulant. Vasomotor and anesthetic effects, are strong. When other
vasoconstrictor drugs, such as ergotamine, simultaneously added, extreme vasospasm, mostly of limbs, and cutaneous injuries, can develop.
We communicate a serious case of cocaine and ergotamine intoxication, followed by necrosis of both legs and one arm. Therefore, the three
extremities must have been to be amputated.
REFERENCES
Ritchie JM, Green NM. Local anesthetics. En Gilman AG, Goodman LS, Gilman A, editors: Goodman and Gilman’s The pharmacological basis of therapeutics, ed. 6. New York 1980, McMillan Publishing Co. Inc. 307-8.
Tomecki KJ, Wikas SM. Cocaine-related bullous disease. J Am Acad. Dermatol 1985; 12: 585- 6.
Vilensky W. Illicit and licit drugs causing perforation of the nasal septum. J Forensic Sci 1982; 27: 958- 62.
Tierney BP, Stadelmann WK. Necrotizing infection of the face secondary to intranasal impaction of “crack” cocaine. Ann Plast Surg 1999; 43: 640 -3.
Virmani R, Robinowitz M, Smialek JE, Smyth DF. Cardiovascular effects of cocaine: an autopsy study of 40 patients. Am Herat J 1989; 117: 1398-9.
Trozak DJ, Gould WM. Cocaine abuse and connective tissue disease. J Am Acad Dermatol 1984; 10: 525.
Nalbandian H, Sheth N, Dietrich R, Georgiou J. Intestinal ischemia caused by cocaine ingestión: report of two cases. Surgery 1985; 97: 374- 6.
Boutros HH, Pautler S, Chakrabarti S. Cocaine induced ischemic colitis with smallvessel trombosis of colon and gallbladder. J Clin Gastroenterol 1997; 24: 49-53.
Eadi MJ. Clinically significant drug interactions with agents specific for migraine attacks. CNS Drugs 2001; 15: 105-18.
Blanche P, Rigolet A, Gombert B, Ginsburg C, et al. Ergotism related to a singledose ergotamine tartrate in an AIDS patient treated with ritonavir. Postgrad Med J 1999; 75: 546 -7.
Halloul Z, Meyer F, Lippert H, Buerger T. Ergotamine-induced acute vasculkar insufficiency of the lower limb. A case report. Angiology 2001; 52: 217-21.
Salvesen R, Prytz JF. Limb-threatening ischemia due to ergotamine: case report with angiographic evidence. Headache 2000; 40: 320 -3.
D’Amore MJ, Borge MA, Messersmith RN. Limb-threatening lower extremity ischemia successfully treated with intraarterial infusión-case reports. Angiology 1999; 50: 233-7.
Dunne JH, Jonson WC. Necrotizing skin lesions in heroin addicts. Arch Derm 1972; 105: 544-7.
Jacobson JM, Hirschman SZ. Necrotizing fasciitis complicating intravenous drug abuse. Arch Intern Med 1982; 142: 634-5.
Heng MCY, Haberfeld G. Thrombotic phenomena associated with intravenous cocaine. J Am Acad Dermatol 1987; 16: 462-8.
Fineschi V, Wetli CV, Di Paolo M, Baroldi G. Myocardial necrosis and cocaine. A quantitative morphologic study in 26 cocaine-associated deaths. Int J Legal Med 1997; 110: 193-8.