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2014, Number 3

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Rev Cubana Hematol Inmunol Hemoter 2014; 30 (3)

Body iron in repetitive donors of a blood bank from Medellìn, Colombia

Mantilla GCY, Pérez R, Cardona AJ

Language: Spanish
References: 36
Page: 233-247
PDF size: 295.15 Kb.


ABSTRACT

Introduction: In blood donors it is important to determine circulated, stored and functional iron; traditionally hemoglobin is the unique measurement included.
Objective: We intended to describe the behavior of iron in repetitive donors according to demographic characteristics as well as iron intake, and its relation to ferritin, hemoglobin and reticulocyte hemoglobin.
Methods: Cross-sectional study of 70 repetitive donors at the University of Antioquía Blood Bank, selected at random. Ferritin, eritrogram, reticulocyte hemoglobin, stool, physical activity and iron dietary were evaluated. Summary measures and frequencies were calculated and the following tests were used: T Student, U of Mann Whitney, H of Kruskal Wallis, Anova and correlations in SPSS.
Results: 60 % of donors were women and the mean age was 33 years old. The median of the erythrocyte parameters evaluated was within reference values; 14.3 % (n= 10) showed iron deficiency and 76.9 % (n= 50) had low iron intake/day. Men got higher values for erythrocyte count, hemoglobin, hematocrit, corpuscular constants and ferritin. Teenagers (18-20 years old) had lower values in intake, reticulocytes and red blood cell distribution width. Ferritin correlated to hemoglobin, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red blood cell distribution width and reticulocyte hemoglobin.
Conclusion: Adequate regulatory mechanisms of iron metabolism with efficient erythropoiesis were evident and we suggest further studies to evaluate nutritional aspects of the blood donors and the feasibility of ferritin determination in regular donors in order to verify adequate reserves to compensate blood caused by donation.


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