medigraphic.com
ISSN 1810-2352 (Print)

2012, Number 2

<< Back Next >>

Rev Cub Med Int Emerg 2012; 11 (2)

Impact of early thrombolytic therapy in reducing mortality from IMA

Martínez RI, Morales GJC, Rodríguez SLA, Rojas BCA

Language: Spanish
References: 21
Page: 2434-2445
PDF size: 180.17 Kb.


ABSTRACT

Introduction: Thrombolysis has become the treatment of AMI. Its specific application in patients has a decisive bearing on prognosis.
Objectives: To evaluate the impact of early thrombolytic therapy in reducing AMI mortality.
Methods: Prospective longitudinal observational study, the universe and the sample were composed of 572 patients with acute myocardial infarction, who were admitted to the intensive care unit.
Results: the clinical form with pain was most common in 92,3 % of patients and it was most frequently located in the anterior face in 42,0 %. 61,3 % classified as Killip- Kimbal (KK) I. In 55,3 % the diagnosis was timely. Thrombolysis was performed in 64,7 % of patients and a leading cause of no-thrombolysis was late diagnosis. 100 % of the discharged patients were aged between 30 and 40 years, their clinical presentation was pain, they were classified as KK I. These patients were timely diagnosed and received thrombolytic therapy.
Conclusions: In the majority of cases, the diagnosis was timely. The highest percent of patients received thrombolytic therapy. Most thrombolyzed patients were classified as KK I. The main cause of no thrombolysis was late diagnosis. Hypotension was the main adverse reaction during and after thrombolysis. The patients who were discharged alive aged 30 and 40, and had pain in their clinical presentation; they were classified as KK I; their diagnosis was timely and received thrombolytic therapy.


REFERENCES

  1. Valdesuso Aguilar RM, Hidalgo Barrios C, León Díaz R, Pérez A. Tratamiento prehospitalario del infarto agudo del miocardio. Rev Cubana cardiol Cir. Cardiovas. 2009; 11(1): p 20-28.

  2. Bartolucci JJ, Animat M, Torres H, Raffo Suazo RL Farmacoepidermiología del infarto agudo del miocardio en el hospital Gustavo fricke. Bol Hosp. 2007; 53(3): 122.

  3. Qureshi AM, Donal L, Primorose WR. Management Of Myocardial infarction in the very elderly – impact of clinical effectiverness on practice. Scott Med J. 2008; 45 (6): p 180 – 182.

  4. Lovesio C. Medicina Intensiva. 5ta Edición. Madrid: Editorial el Ateneo; 2002.

  5. Karliner JS, Gregoratos G, Ross JJ. Infarto de miocardio. En: Stein JH. Medicina Interna. Edición revolucionaria. Ciudad de la Habana: Editorial Científico Técnica; 1987. p 460-470.

  6. Alpert JS, Braunwald E. Anatomía Patológica y manifestaciones clínicas del infarto. En: Braunwald E. Tratado de cardiología. 11a edición. Ciudad de la Habana: Editorial Científico Técnica; 2008. p1472- 1473.

  7. Pasternar RC, Braunwald E, Alpert JS. Infarto agudo del miocardio. En: Braunwald E, Isselbacher KJ, Petersdurf RC, Wilson JD, Martín JB, Fauci AS, et al. Principios de Medicina Interna. 11a edición. México: Editorial Interamericana; 1989. p 1504- 1510.

  8. Sobel Burton E. Infarto agudo del miocardio. En: Claude Bennett J. Cecil tratado de Medicina interna. 20a edición. La habana. Editorial ciencias médicas; 1998. p 344-360.

  9. Pollard JJ. The acute myocardial infarction. Prim Care 2009; 27(3): p 631- 49.

  10. Victor C, Eterov D. Symptom presentation of acute myocardial infarction: Influence of sex age, and risk factors. American Heart Journal. 2007; 144(6) p1012-1017.

  11. Then KL, Rankin JA, poforoff DA. Atypical presentation of acute myocardial infarction in 3 age groups. Heart Lung. 2008; 30(4): p 285-293.

  12. Valdespino A, Solorio S, Baduí E, Ocaña J, Ayala F. Primer infarto agudo del Miocardio en el anciano. Arch Inst. cardiol. Méx. 2004; 64 (6): p 551-555.

  13. Escobar JL, Benites O, Velasco MF, Villanueva HE. Morbimortalidad del Infarto Agudo del Miocardio en el HPAS. Estudio Ibérica. Med Clin. 2009; 115 (14): p 45- 50.

  14. Woon VC, Lim KH. Acute myocardial infarction in the elderly – the differences compared with The young. Singapore Med Journal. 2009;44(8):p 414-418.

  15. Sweeney JC, Cody M, Crane PB. Do you Know them when you see them women prodromal and acute symptoms of myocardial infarction. J Cardiovasc Nurs. 2008; 15(3):p 26-38.

  16. Sweeney JC. Women early warning symptoms of acute myocardial infarction. Circulation. 2007; 108 (21): p 2619 - 2623.

  17. 12Farreras R. Tratado de Medicina Interna. [CD – ROM]. 14 ed. Madrid: Editorial Médica Panamericana; 2000.

  18. Pariona M, Rivera G. Complicaciones intrahospitalaria del infarto de miocardio Agudo transmural en el servicio de cardiología del hospital nacional Edgardo Rebagliati Martins. An fac Med. 2008; 57(1): 14-21.

  19. Martín Jadraque L, Coma Canella I, González Maqueda, López Sendon JL. Cardiopatía isquémica. Edición revolucionaria. La Habana: Editorial Científicotécnica; 1984.

  20. Trujillo Salgado IE. Alteraciones cardiacas en la insuficiencia renal crónica. Correlación clínico- patológica. Rev. Cubana Cardiol. 2007; 11 (7): p 65-73.

  21. Quilon K. Myocardial infarction presenting as Stroke. J assoc physicians India. 2008; 46(7): p 613-615.




2020     |     www.medigraphic.com