Pérez-Rivero JJ, Aguilar-Setién A, Villa-Godoy A, Serrano H

Language: English/Spanish
References: 15
Page: 469-474
PDF size: 349.50 Kb.

ABSTRACT

Desmodus rotundus is the most important vector for bovine paralytic rabies (BPR). Campaigns for controlling its population in Mexico are not satisfactory, since the BPR national reports for 2004 show an increase in the number of BPR cases in many states. The current strategy for controlling D. rotundus is to kill as many individuals as possible by the application of a warfarin ointment to captured animals, which spread the drug to other members of the colony during grooming activities. At present, a new no-killing culture is predominant throughout the world, for which new control methods are required to maintain populations of pest low. Based on data obtained from rodents, in which reproductive alterations were induced by phytoestrogens, we are developing a method to induce infertility with coumestrol in D. rotundus. In this short communication, we are reporting the initial demonstration by fluorescence that coumestrol binds to estrogen receptor β in testis of D. rotundus. This finding is an evidence that coumestrol is a potential agent for reproductive control for vampires.

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