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2005, Número 4

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Vet Mex 2005; 36 (4)


Papel de los receptores tipo toll en la inmunidad innata y su implicación en medicina veterinaria

Bautista GCR, Mosqueda GJJ

Idioma: Español/Inglés
Referencias bibliográficas: 96
Paginas: 453-468
Archivo PDF: 516.11 Kb.


RESUMEN

El concepto de inmunidad innata ha tenido un cambio notable durante los últimos cinco años, debido al descubrimiento de los receptores tipo Toll (TLR, proteínas transmembranales expresadas por células del sistema inmunitario innato) en los mamíferos y su participación en el reconocimiento de patógenos microbianos. Actualmente el estudio de estos receptores es de gran interés, sobre todo en medicina humana y muy recientemente en medicina veterinaria, debido a que desempeñan un papel central, tanto en el desencadenamiento de la inmunidad innata, como en la coordinación entre las inmunidades innata y adaptativa. Esta revisión pretende mostrar el concepto del papel de los receptores tipo Toll en los procesos de inmunidad desde la perspectiva de su importancia en medicina veterinaria.


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