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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2014, Number 2

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Bol Clin Hosp Infant Edo Son 2014; 31 (2)

Systemic Erythematosus Disseminated Lupus in Children.

Olmos-García FX, Suárez-Larios LM, Velázquez-Contreras CA, Sotelo-Cruz N, Manjarrez-Orduño N

Language: Spanish
References: 29
Page: 101-106
PDF size: 61.05 Kb.


ABSTRACT

Systemic lupus erythematosus (SLE) is an autoimmune chronic disease, with a higher incidence in females of reproductive age, particularly of African and Asian background. SLE is characterized by the presence of autoantibodies and by the deposition of antigen-antibody complexes in some organs. Quantification of autoreactive antibodies, including anti-nuclear antibody is one of the criteria for diagnosis.
In rare circumstances when lupus appears in children, it is aggressive and acute, with variations in the gender preference, clinical and prognosis manifestations. Because of the low frequency, the clinical management of these patients is complicated, and special and specific measures are required different from those of adults.
In this review the main clinical aspects of pediatric lupus are addressed, such as diagnosis, prognosis, treatment, clinical manifestations, among others, while compared with the adult counterpart of this disease.


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