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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2014, Number 3

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An Med Asoc Med Hosp ABC 2014; 59 (3)

Neurocysticercosis and epilepsy

San-Juan OD, Rodríguez ZE, Gómez GGJ, Vázquez GR, Tabera TPM, Fleury A

Language: Spanish
References: 50
Page: 212-218
PDF size: 194.93 Kb.


ABSTRACT

Human neurocysticercosis is recognized as a public health problem, being considered the most frequent parasitosis of the central nervous system. In Mexico, neurocysticercosis constitutes the main cause of new-onset epilepsy in adults. The clinical presentations are varied, epilepsy is one of the most common clinical manifestations and its frequency varies from 60 to 90%. Seizures occur in approximately 80% of patients with neurocysticercosis, and they may be present throughout any stage of neurocysticercosis, the colloidal transition stage being the most epileptogenic. The type of seizure is related to the number and localization of the parasites. Diagnostic accuracy and its classification are frequently limited by neuroimaging and neurophysiology resources. Treatment of symptomatic epilepsy is based on the general guidelines for the treatment of epilepsy, without considering the particularities of neurocysticercosis. The aim of this review is to show the clinical manifestations, classification, physiopathology, diagnosis and treatment of epilepsy due to neurocysticercosis. Currently, there is a lack of information about long-term outcome, underlying epileptogenic mechanisms, the efficacy and security of new antiepileptics, including some first generation AEs.


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