2014, Number 3
<< Back Next >>
Rev Mex Anest 2014; 37 (3)
Perioperative management of hyperthermic intraperitoneal chemotherapy
Carrillo-Esper R, Nava-López JA, Romero-Sierra G, Cáñez-Jiménez C
Language: Spanish
References: 25
Page: 193-200
PDF size: 223.46 Kb.
ABSTRACT
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) has become the standard treatment for patients with tumors of the peritoneal surface. Completion of this combined procedure can last up to more than 13 hours during which alterations as hydroelectrolyte imbalance, hypovolemia, coagulopathy, changes in temperature and metabolism, as well as changes in lung function are presented. The technique for the administration of intraperitoneal therapy has its own risks, mainly cardiovascular, especially with the closed technique. The perioperative management should be individualized according to the needs of each patient and use the monitoring to adapt and optimize the mechanical ventilation, fluid replacement, coagulation and hemodynamic status. The use of combined general and regional anesthesia improves the prognosis of patients, however not all are candidates for neuraxial blockade. The aim of this review is that the anesthesiologist knows the process of HIPEC and alterations that may occur in the perioperative period to prevent and treat them in a timely manner.
REFERENCES
Bell JC, Rylah BG, Chambers RW, Peet H, Mohamed F, Moran BJ. Perioperative management of patients undergoing cytoreductive surgery combined with heated intraperitoneal chemotherapy for peritoneal surface malignancy: a multi-institutional experience. Ann Surg Oncol. 2012;19:4244-4251.
Chua TC, Robertson G, Liauw W, Farrell R, Yan TD, Morris DL. Intraoperative hyperthermic intraperitoneal chemotherapy after cytoreductive surgery in ovarian cancer peritoneal carcinomatosis: systematic review of current results. J Cancer Res Clin Oncol. 2009;135:1637-1645.
Schmidt C, Creutzenberg M, Piso P, Hobbhahn J, Bucher M. Peri-operative anaesthetic management of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Anaesthesia. 2008;63:389-395.
Piso P, Schmidt C, Wiesenack C, Bucher M, Schlitt HJ, Graf BM. Particularities of anesthesia and postoperative intensive care related to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy [Internet]. Timisoara. 2009 [Citado el 2014 Feb];815-820. Disponible en: http://www.atitimisoara.ro/_files/documents/files/2009/Actualitati%20ATI%20si%20Medicina%20de%20Urgenta%202009/Particularities%20of%20anesthesia%20and%20postoperative%20intensive%20care%20related%20to%20cytoreductive%20surgery%20a.pdf
Cooksley TJ, Haji-Michael P. Post-operative critical care management of patients undergoing cytoreductive surgery and heated intraperitoneal chemotherapy (HIPEC). World J Surg Oncol. 2011;9:169.
Gill RS, Al-Adra DP, Nagendran J, Campbell S, Shi X, Haase E, et al. Treatment of gastric cancer with peritoneal carcinomatosis by cytoreductive surgery and HIPEC: a systematic review of survival, mortality, and morbidity. J Surg Oncol. 2011;104:692-698.
González-Moreno S, Ortega-Pérez G, González-Bayón L. Indications and patient selection for cytoreductive surgery and perioperative intraperitoneal chemotherapy. J Surg Oncol. 2009;100:287-292.
Kanakoudis F, Petrou A, Michaloudis D, Chortaria G, Konstantinidou A. Anaesthesia for intra-peritoneal perfusion of hyperthermic chemotherapy. Haemodynamic changes, oxygen consumption and delivery. Anaesthesia. 1996;51:1033-1036.
Thix CA, Königsrainer I, Kind R, Wied P, Schroeder TH. Ventricular tachycardia during hyperthermic intraperitoneal chemotherapy. Anaesthesia. 2009;64:1134-1136.
la Chapelle de A, Perus O, Soubielle J, Raucoules-Aime M, Bernard JL, Bereder JM. High potential for epidural analgesia neuraxial block-associated hypotension in conjunction with heated intraoperative intraperitoneal chemotherapy. Regional Anesthesia and Pain Medicine. 2005;30:313-314.
Wulf H. Epidural anaesthesia and spinal haematoma. Can J Anaesth. 1996;43:1260-1271.
Horlocker TT, Wedel DJ, Benzon H, Brown DL, Enneking FK, Heit JA, et al. Regional anesthesia in the anticoagulated patient: defining the risks (the second ASRA Consensus Conference on Neuraxial Anesthesia and Anticoagulation). Regional Anesthesia and Pain Medicine. 2003;28:172-197.
Desgranges F-P, Steghens A, Mithieux F, Rosay H. Potential risks of thoracic epidural analgesia in hyperthermic intraperitoneal chemotherapy. J Surg Oncol. 2010;101:442.
Cafiero T, Di Iorio C, Di Minno RM, Sivolella G, Confuorto G. Non-invasive cardiac monitoring by aortic blood flow determination in patients undergoing hyperthermic intraperitoneal intraoperative chemotherapy. Minerva Anestesiol. 2006;72:207-215.
Hofer CK, Senn A, Weibel L, Zollinger A. Assessment of stroke volume variation for prediction of fluid responsiveness using the modified FloTracTM and PiCCOplusTM system. Crit Care. 2008;12:R82.
Marik PE. Does central venous pressure predict fluid responsiveness? Chest. 2008;134:172.
Jonas M, Fennell J, Brudney CS. Haemodynamic management in major surgery [Internet]. Anaesthesia International. 2008 [Citado el 2014 Feb];2(1):1-6. Disponible en: http://www.lidcorapid.co.uk/pdfs/jonas-m-et-al-ai-2008.pdf
Arakelian E, Gunningberg L, Larsson J, Norlén K, Mahteme H. Factors influencing early postoperative recovery after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. European Journal of Surgical Oncology. 2020;37:897-903.
Vorgias G, Iavazzo C, Mavromatis J, Leontara J, Katsoulis M, Kalinoglou N, et al. Determination of the necessary total protein substitution requirements in patients with advanced stage ovarian cancer and ascites, undergoing debulking surgery. Correlation with plasma proteins. Ann Surg Oncol. 2007;14:1919-1923.
Schols SEM, Lance MD, Feijge MAH, Damoiseaux J, Marcus MA, Hamulyak K, et al. Impaired thrombin generation and fibrin clot formation in patients with dilutional coagulopathy during major surgery. Thromb Haemost. 2010;103:318-328.
Smeenk RM, Verwaal VJ, Zoetmulder FAN. Toxicity and mortality of cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in pseudomyxoma peritoneia report of 103 procedures. European Journal of Surgical Oncology. 2006;32:186-190.
Ahmed S, Oropello JM. Critical care issues in oncological surgery patients. Critical Care Clinics. 2010;26:93-106.
Bielen R, Verswijvel G, Van der Speeten K. Rhabdomyolysis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a case report. Case Rep Oncol. 2013;6:36-44.
McConnell YJ, Mack LA, Francis WP, Ho T, Temple WJ. HIPEC + EPIC versus HIPEC-alone: Differences in major complications following cytoreduction surgery for peritoneal malignancy. J Surg Oncol. 2012;107:591-596.