2014, Number 3
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Acta Med Cent 2014; 8 (3)
Effectiveness of calendula tincture to 20% in dermatological conditions
Hurtado PA, Castro GM, Blanco PL
Language: Spanish
References: 18
Page: 28-36
PDF size: 111.75 Kb.
ABSTRACT
A quasi-experimental, prospective, longitudinal study was conducted at the
National Hospital of Nebaj, Guatemala, during the period December 2011 to
December 2012 to determine the effectiveness of calendula tincture to 20% in
the treatment of furunculosis and contact dermatitis and atopic. Patients
previously diagnosed by a Specialist in General Medicine in the outpatient
formed the study population; the sample was selected by purposive sampling
method and patients were divided into study group (calendula tincture to 20%)
and control group (conventional medicine). At the beginn, they were
evaluating, seven, 14 and 21 days and the clinical outcome were observed,
recovery time and adverse reactions to treatment. In 88.1% of patients in the
study group had successful outcomes dermal lesions compared with 71.4% in
the control group; all patients with boils in the study group were recovered
from seven to 14 days of treatment, as opposed to 80% in the control group;
with calendula tincture to 20% presented adverse reactions in 2.4% of patients
with conventional treatment in 26.2%. The treatment in the study group was
effective in 88.1% of patients while in the control group was effective in 66.7%;
differences were significant (p = 0.04). Calendula tincture to 20% was effective
in the treatment of furunculosis and contact and atopic dermatitis.
REFERENCES
Cuba. Ministerio de Salud Pública. Plantas medicinales y medicamentos herbarios. Disciplina Farmacología. Programa área de docencia. La Habana: MINSAP; 1996.
Danielski L, Campos LMAS, Bresciani LFV, Hense H, Yunes RA, Ferreira SRS. Marigold (Calendula officinalis L.) oleoresin: Solubility in SC-CO2 and composition profile. Chem Eng Process. 2007;46(2):99–106.
Nunes LF. Assessment of plant development, morphology and flavonoid content in different cultivation treatments of Calendula officinalis L. Rev Bras Farmacog. 2010;20(6):974-80.
Leal LM, Andrade MA, Batista LA, Brianezi VM, Pacheco M, De Souza R, et al. Atividade angiogênica das flores da Calendula officinalis L. em ratos. Acta Cir Bras [Internet] 2011 Jan-Feb [citado 2 Ago 2013];26(1):[aprox. 4 p.]. Disponible en: www.scielo.br/scielo.php?script=sci_arttext&pid=S0102
Parente L, Silva M, Brito L, Lino-Júnior R, Paula J, Trevenzol L, et al. Efeito cicatrizante e atividade antibacteriana da Calendula officinalis L. cultivada no Brasil. Rev Bras Plantas Med [Internet]. 2009 [citado 2 Ago 2013];11(4):[aprox. 4 p.]. Disponible en: www.scielo.br/scielo.php?script=sci_arttext&pid=S1516
Medina E, Garcia-Lora A, Paco L, Algarra I, Collado A, Garrido F. A new extract of the plant calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation. BMC Cancer. 2006;6:119.
Szakiel A, Ruszkowski D, Grudniak A, Kurek A, Wolska KI, Doligalska M, et al. Antibacterial and antiparasitic activity of oleanolic acid and its glycosides isolated from marigold (Calendula officinalis). Planta Med. 2008 Nov;74(14):1709-15 doi: 10.1055/s-0028-1088315.
Fuchs SM, Schliemann-Willer S, Fisher TW, Elsner P. Protective effects of different marigold (Calendula officinalis L.) and rosemary cream preparations against sodium-laurylsulphate- induced irritant contact dermatitis. Skin Pharmacol Physiol. 2005;18:195–200.
Chandran PK, Kuttan R. Effect of Calendula officinalis Flower Extract on Acute Phase Proteins, Antioxidant Defense Mechanism and Granuloma Formation During Thermal Burns. J Clin Biochem Nutr. 2008;43(2):58-64. doi: 10.3164/jcbn.2008043.
Basch E, Bent S, Foppa I. Marigold (Calendula officinalis L.): an evidence-based systematic review by the Natural Standard Research Collaboration. J Herb Pharmacother. 2006;6(3-4):135-59.
Preethi KC, Kuttan G, Kuttan R. Anti-inflammatory activity of flower extract of Calendula officinalis Linn. and its possible mechanism of action. Indian J Exp Biol. 2009 Feb;47(2):113-20.
Denardi L, Bortolin K, Dias J. Topical Calendula officinalis L. successfully treated exfoliative cheilitis: a case report. Cases J. 2009 Nov 23;2:9077. doi: 10.1186/1757-1626-2-9077
Preethi KC, Kuttan R. Wound healing activity of flower extract of Calendula officinalis. J Basic Clin Physiol Pharmacol. 2009;20(1):73-9.
Radioza SA, Iurchak LD. Antimicrobial activity of Calendula L. plants. Mikrobiol Z. 2007 Sep-Oct;69(5):21-5.
Martínez M, Pérez E, Castro J. Piodermitis, tratamiento con Tintura de Caléndula 20 %. Gac Méd Espirit [Internet]. 2003 [citado 2 Ago 2013];5(3):[aprox. 4 p.]. Disponible en: http://bvs.sld.cu/revistas/gme/pub/vol.5.%283%29_04/resumen.html
Pommier P, Gomez F, Sunyach MP, D’Hombres A, Carrie C, Montbarbon X. Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. Clin Oncol. 2004 Apr 15;22(8):1447-53.
Ávila J, Jiménez G, González B, Morón F, Fernández R. Reacciones adversas a medicamentos herbarios y otras formas de medicina natural y tradicional en Cuba durante 2001-2004. Rev Cubana Plant Med. 2008;13(1):33-7.
Braga PC, Dal Sasso M, Culici M, Spallino A, Falchi M, Bertelli A. Antioxidant Activity of Calendula officinalis Extract: Inhibitory Effects on Chemiluminescence of Human Neutrophil Bursts and Electron Paramagnetic Resonance Spectroscopy. Pharmacology. 2009;83:348–55.